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Gene Expression Data
Assay Details
Assay
Reference: J:75937 Damert A, et al., Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development. 2002 Apr;129(8):1881-92
Assay type: RNA in situ
MGI Accession ID: MGI:2446618
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Probe: VEGFR2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen VEGFR2 E8.0 +/+: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Present 3VEGFR2 8.0 +/+
Specimen VEGFR2 E8.0 -/-: embryonic day 8.0; Vegfatm2.1Nagy/Vegfatm2.1Nagy (more )
Structure Level Pattern Image Note
TS12: embryo Present 3VEGFR2 8.0 -/-
Specimen VEGFR2 E9.0 +/+: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: head Weak 3VEGFR2 9.0 +/+ bottom , 3VEGFR2 9.0 +/+ middle
TS14: cardiovascular system Weak Regionally restricted 3VEGFR2 9.0 +/+ middle , 3VEGFR2 9.0 +/+ bottom Authors state that expression is low in the intersomitic vessels.
Specimen VEGFR2 E9.0 -/-: embryonic day 9.0; Vegfatm2.1Nagy/Vegfatm2.1Nagy (more )
Structure Level Pattern Image Note
TS14: head Weak 3VEGFR2 9.0 -/- bottom , 3VEGFR2 9.0 -/- middle
TS14: cardiovascular system Weak Regionally restricted 3VEGFR2 9.0 -/- middle , 3VEGFR2 9.0 -/- bottom Authors state that expression is low in the intersomitic vessels.
Specimen 4A: embryonic day 9.0 (more )
Note: Text and fig. legend disagree on embryo stage. Text states E 8.5 and legend states E9.0. E9.0 was used as stage.
Structure Level Pattern Image Note
TS14: cardinal vein Present 4A
TS14: heart Present Regionally restricted 4A Authors state expression detected in the endocardium.
Specimen 4B: embryonic day 9.0; Vegfatm2.1Nagy/Vegfatm2.1Nagy (more )
Note: Text and fig. legend disagree on embryo stage. Text states E 8.5 and legend states E9.0. E9.0 was used as stage.
Structure Level Pattern Image Note
TS14: cardinal vein Weak 4B Expression is much lower than in wild type.
TS14: heart Weak Regionally restricted 4B Authors state expression detected in the endocardium and is much lower than in wild type.
Specimen 4C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 4C Expression detected in the endothelial lining of blood islands in the yolk sac.
Specimen 4D: embryonic day 9.0; Vegfatm2.1Nagy/Vegfatm2.1Nagy (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 4D Expression detected in the endothelial lining of blood islands in the yolk sac.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory