Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:82457
Ligon KL, et al., Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development. 2003 May;130(10):2275-87
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:2673725
|
|
Gene symbol:
|
Nes
|
|
Gene name:
|
nestin
|
|
|
Results
|
Specimen
7G:
embryonic day 18.5
(more  )
Specimen
7G:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex |
Present |
Single cells |
7G
|
Expression was detected in the radial glial foot processes forming the glia limitans.
|
Specimen
7H:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Emx2tm1Pgr/Emx2tm1Pgr
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex |
Present |
Single cells |
7H
|
In the mutant, expression was detected normally in the radial glial foot processes forming the glia limitans outside of the heterotopias.
|
| TS26: cerebral cortex marginal zone |
Present |
Single cells |
7H
|
In the lesions, abnormal radial glial processes extended throughout the subplate and marginal zone.
|
|
Analysis Tools