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Gene Expression Data
Assay Details
Assay
Reference: J:85472 Kawahira H, et al., Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct;130(20):4871-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2675743
Gene symbol: Ins2
Gene name: insulin II
Antibody: anti-insulin # 4011-01
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Antibody specificity was not provided; both family members have been annotated.
Results
Specimen 3C: embryonic day 18.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Amy (assay MGI:2675742).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 3C

Specimen 3D: embryonic day 18.5; Hhiptm1Amc/Hhiptm1Amc (more )
Note: Double labeled: green - Ins1 and Ins2; red - Amy (assay MGI:2675742).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 3D

Specimen 4A: embryonic day 18.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Gcg (assay MGI:2675746).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 4A Clusters of insulin-positive cells.

Specimen 4B: embryonic day 18.5; Hhiptm1Amc/Hhiptm1Amc (more )
Note: Double labeled: green - Ins1 and Ins2; red - Gcg (assay MGI:2675746).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present Regionally restricted 4B Clusters of insulin-positive cells are significantly smaller than in wild-type.

Specimen 4F: embryonic day 18.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Pdx1 (assay MGI:2675749).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 4F

Specimen 4G: embryonic day 18.5; Hhiptm1Amc/Hhiptm1Amc (more )
Note: Double labeled: green - Ins1 and Ins2; red - Pdx1 (assay MGI:2675749).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 4G

Specimen 4H: embryonic day 18.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Slc2a2 (assay MGI:2675751).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 4H

Specimen 4I: embryonic day 18.5; Hhiptm1Amc/Hhiptm1Amc (more )
Note: Double labeled: green - Ins1 and Ins2; red - Slc2a2 (assay MGI:2675751).
Structure Level Pattern Image Note
TS26: islets of Langerhans Present 4I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory