Dlx5 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:87163 Zhang Z, et al., Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79
Assay type:	RNA in situ
MGI Accession ID:	MGI:3028936
Gene symbol:	Dlx5
Gene name:	distal-less homeobox 5

Probe:	Dlx5 probe1
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2G ©

Specimen Dlx5 E14.5: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: lower jaw molar mesenchyme	Present	Uniform	2G	Expression is in the dental papilla and the dental follicle.
TS22: upper jaw molar mesenchyme	Present	Uniform	2G	Expression is in the dental papilla and the dental follicle.
TS22: lower jaw skeleton	Present	Regionally restricted	2G	Expression is in the alveolar bone.
TS22: upper jaw skeleton	Present	Regionally restricted	2G	Expression is in the alveolar bone.
TS22: lower jaw molar epithelium	Present		2G
TS22: upper jaw molar epithelium	Present		2G

2H ©

Specimen Dlx5 E16.5: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: lower jaw molar mesenchyme	Present	Uniform	2H	Expression is in the dental papilla and the dental follicle.
TS24: upper jaw molar mesenchyme	Present	Uniform	2H	Expression is in the dental papilla and the dental follicle.
TS24: lower jaw skeleton	Present	Regionally restricted	2H	Expression is in the alveolar bone.
TS24: upper jaw skeleton	Present	Regionally restricted	2H	Expression is in the alveolar bone.
TS24: lower jaw molar epithelium	Present		2H
TS24: upper jaw molar epithelium	Present		2H

3C ©

Specimen Dlx5 wt: embryonic day 13.5 (more

)

Structure	Level	Image
TS21: lower jaw molar mesenchyme	Present	3C
TS21: upper jaw molar mesenchyme	Present	3C
TS21: lower jaw molar epithelium	Present	3C
TS21: upper jaw molar epithelium	Present	3C

3D ©

Specimen Dlx5 msx1 -/-: embryonic day 13.5; Msx1^tm1Rilm/Msx1^tm1Rilm (more

)

Structure	Level	Image
TS21: lower jaw molar mesenchyme	Absent	3D
TS21: upper jaw molar mesenchyme	Absent	3D
TS21: lower jaw molar epithelium	Present	3D
TS21: upper jaw molar epithelium	Present	3D

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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