Gene Expression Data
Assay Details
Assay
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Reference:
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J:54095
Inada M, et al., Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3043259
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Gene symbol:
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Bmp6
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Gene name:
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bone morphogenetic protein 6
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Probe:
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BMP6 probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5 +/+ tibia BMP6:
embryonic day 18.5
(more )
Specimen
5 +/+ tibia BMP6:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS26: tibia |
Present |
Regionally restricted |
5+/+ tibia Bmp6
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Expression was detected in prehypertrophic and hypertrophic chondrocytes but was weak in terminal hypertrophic chondrocytes.
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Specimen
5 -/- tibia BMP6:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Runx2tm1Kish/Runx2tm1Kish
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Age:
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embryonic day 18.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: tibia |
Weak |
Regionally restricted |
5-/- tibia Bmp6
|
Expression was weak in prehypertrophic and hypertrophic chondrocytes and was decreased in terminal hypertrophic chondrocytes.
|
Specimen
5 -/- femur BMP6:
(close )
Genetic Background:
|
involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
|
Runx2tm1Kish/Runx2tm1Kish
|
Age:
|
embryonic day 18.5
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
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Not Specified
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Type:
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section
|
|