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Gene Expression Data
Assay Details
Assay
Reference: J:91057 Louvi A, et al., Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105
Assay type: RNA in situ
MGI Accession ID: MGI:3052334
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Results
Specimen 7A Math1 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Present Regionally restricted 7A Expression is in the external granule layer.

Specimen 7B: embryonic day 17.5; Psen1tm1Pcw/Psen1tm1Pcw (more )
Structure Level Pattern Image Note
TS25: cerebellum Present Regionally restricted 7B Granule cell precursor generation and spreading are compromised in this mutant.

Specimen 9A Math1 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Present 9A E11.5

Specimen 9A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present 9A E13.5 Expression is weaker medially.

Specimen 9A E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebellum Present Regionally restricted 9A E14.5 Expressing cells are spreading over the cerebellum.

Specimen 9B (top): embryonic day 11.5; Psen1tm1Pcw/Psen1tm1Pcw (more )
Structure Level Pattern Image Note
TS19: cerebellum primordium Strong 9B top Expression is enhanced in this mutant.

Specimen 9B (middle): embryonic day 13.5; Psen1tm1Pcw/Psen1tm1Pcw (more )
Structure Level Pattern Image Note
TS21: cerebellum Strong 9B middle Expression is not down-regulated medially.

Specimen 9B (bottom): embryonic day 14.5; Psen1tm1Pcw/Psen1tm1Pcw (more )
Structure Level Pattern Image Note
TS22: cerebellum Present Regionally restricted 9B bottom In this mutant, expressing cells accumulate medially rather than spreading over the cerebellum.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory