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Gene Expression Data
Assay Details
Assay
Reference: J:93571 Rowan S, et al., Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
Assay type: RNA in situ
MGI Accession ID: MGI:3525945
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Probe: p57 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E14.5 heterozygote: embryonic day 14.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted S1N E14.5 orJ/+ Expression is present in the periphery of the retina (zones 1 and 2).
TS22: pigmented retinal epithelium Absent S1N E14.5 orJ/+

Specimen E14.5 homozygote: embryonic day 14.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted S1N E14.5 orJ/orJ Expression was highly upregulated in the peripheral retina and expressed at lower levels in more central parts.

Specimen E17.5 heterozygote: embryonic day 17.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS25: neural retina Present Regionally restricted S1N E17.5 orJ/+ Expression is present in the periphery of the retina (zones 1 and 2).

Specimen E17.5 homozygote: embryonic day 17.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS25: retina Present S1N E17.5 orJ/orJ Expression is highly upregulated throughout the entire retina.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory