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Gene Expression Data
Assay Details
Assay
Reference: J:93571 Rowan S, et al., Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
Assay type: RNA in situ
MGI Accession ID: MGI:3526439
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: pOtd9
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E14.5 heterozygote: embryonic day 14.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present S1R E14.5 orJ/+ Expression is present in both the outer neuroblast layer and retinal pigmented epithelium, including zone 3, but not in the peripheral retina.
TS22: pigmented retinal epithelium Present S1R E14.5 orJ/+ Expression is present in both the outer neuroblast layer and retinal pigmented epithelium, including zone 3, but not in the peripheral retina.
Specimen E14.5 homozygote: embryonic day 14.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS22: retina Present S1R E14.5 orJ/orJ There is ectopic expression in the retina. It includes expression in lightly pigmented cells in the peripheral retina.
Specimen E17.5 heterozygote: embryonic day 17.5; Vsx2or-J/Vsx2+ (more )
Structure Level Pattern Image Note
TS25: pigmented retinal epithelium Present S1R E17.5 orJ/+
Specimen E17.5 homozygote: embryonic day 17.5; Vsx2or-J/Vsx2or-J (more )
Structure Level Pattern Image Note
TS25: retina Present S1R E17.5 orJ/orJ
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory