Gene Expression Data
Assay Details
Assay
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Reference:
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J:75058
Davies D, et al., Differential expression of alpha3 and alpha6 integrins in the developing mouse inner ear. J Comp Neurol. 2002 Apr 1;445(2):122-32
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3575632
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Gene symbol:
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Itga6
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Gene name:
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integrin alpha 6
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Results
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Specimen
1A,B:
embryonic day 10.5
(more )
Specimen
1A,B:
(close )
Genetic Background:
|
C57BL/6
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Age:
|
embryonic day 10.5
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: otocyst epithelium |
Present |
Non-Uniform |
1B
,
1A
|
Expression is throughout the epithelium, but is intense in the anteriolateral region of the mid-otocyst. This coincides with the area of neuroblast delamination. Expression appears to be in neuroblast precursors that have not yet delaminated.
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TS17: acoustic ganglion |
Present |
Single cells |
1A
,
1B
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The expression does not seem to be in the same cells that express Neurod1 (see assay MGI:3575640).
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TS17: facial ganglion |
Present |
Single cells |
1A
,
1B
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The expression does not seem to be in the same cells that express Neurod1 (see assay MGI:3575640).
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Specimen
2B:
embryonic day 12.5
(more )
Specimen
2B:
(close )
Genetic Background:
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C57BL/6
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Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: inner ear vestibular component |
Present |
Regionally restricted |
2B
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Expression is in the prosensory regions of the ampulla. There seems to be a reciprocal staining of Itga6 and Itga3 (see assay MGI:3575638).
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Specimen
2D:
embryonic day 12.5
(more )
Specimen
2D:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3A:
embryonic day 12.5
(more )
Specimen
3A:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: inner ear vestibular component |
Present |
Regionally restricted |
3A
|
Staining in the ampulla is in the same area as nerve fibers that penetrate the epithelium.
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Specimen
4B:
embryonic day 14.5
(more )
Specimen
4B:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: inner ear vestibular component |
Present |
Regionally restricted |
4B
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Expression is in the sensory areas of the ampulla and the fibers supplying them. Staining is in clearly delineated patches corresponding to cuticular plates and immature hair bundles.
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TS22: inner ear |
Present |
Regionally restricted |
4B
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Expression is throughout the epithelial-mesenchymal border.
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Specimen
4E:
embryonic day 14.5
(more )
Specimen
4E:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: cochlear duct epithelium |
Present |
Regionally restricted |
4E
|
Expression is in the sensory areas and the fibers supplying them.
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TS22: inner ear |
Present |
Regionally restricted |
4E
|
Expression is throughout the epithelial-mesenchymal border.
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Specimen
5B:
embryonic day 18.5
(more )
Specimen
5B:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: inner ear vestibular component |
Present |
Non-Uniform |
5B
|
Expression is in the sensory epithelium of the ampulla. Expression is in the greater epithelial ridge, the spiral limbus and beneath the support cells.
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Specimen
5E:
embryonic day 18.5
(more )
Specimen
5E:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
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Specimen
6A:
embryonic day 18.5
(more )
Specimen
6A:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cochlea |
Present |
Regionally restricted |
6A
|
Expression is in spiral ganglion fibers beneath all sensory areas. Expression is also within the cell bodies of the spiral ganglion. Staining in the epithelium itself does not seem to be associated with nerve fibers.
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Specimen
7B:
postnatal day 0
(more )
Specimen
7B:
(close )
Genetic Background:
|
C57BL/6
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Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
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Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: inner ear vestibular component |
Strong |
Regionally restricted |
7B
|
Expression is in the support cell and hair cell layers within the sensory epithelia of the crista and utricular macula, but is absent in the nonsensory epithelium connecting them.
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TS27: utricle |
Strong |
Regionally restricted |
7B
|
Expression is in the support cell and hair cell layers within the sensory epithelia of the crista and utricular macula, but is absent in the nonsensory epithelium connecting them.
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Specimen
7E:
postnatal day 0
(more )
Specimen
7E:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: cochlear duct |
Present |
Regionally restricted |
7E
|
Expression is in the sensory epithelia and the fibers from the spiral ganglion.
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Specimen
8D:
postnatal day 6
(more )
Specimen
8D:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 6
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: saccule |
Present |
Regionally restricted |
8D
|
Expression is in the fibers beneath the sensory epithelium, but is not in the epithelium itself.
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Specimen
8E:
postnatal day 6
(more )
Specimen
8E:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 6
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Weak |
Regionally restricted |
8E
|
Expression is in the sensory epithelium of the basal turn.
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Specimen
8F:
postnatal day 6
(more )
Specimen
8F:
(close )
Genetic Background:
|
C57BL/6
|
Age:
|
postnatal day 6
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: organ of Corti |
Moderate |
Regionally restricted |
8F
|
Expression is in the sensory epithelium of the apex.
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|