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Gene Expression Data
Assay Details
Assay
Reference: J:95331 Daniel D, et al., Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem. Gene Expr Patterns. 2005 Feb;5(3):317-22
Assay type: RNA in situ
MGI Accession ID: MGI:3576598
Gene symbol: Cxcl12
Gene name: C-X-C motif chemokine ligand 12
Probe: SDF-1-alpha-cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Not Shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Strong Regionally restricted Expression is in the meninges, absent in the cortical parenchyme.

Specimen 1A: embryonic day 12.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS20: cerebral cortex intermediate zone Present Regionally restricted 1A Expression is in a small part of the intermediate zone close to the pallial-subpallial boundary, absent in the subpallium.
TS20: telencephalon Present Regionally restricted 1A Expression is in a small part of the intermediate zone close to the pallial-subpallial boundary, absent in the subpallium.

Specimen 1B: embryonic day 13.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS21: telencephalon meninges Strong 1B
TS21: cerebral cortex Present Regionally restricted 1B Expression is from the pallial-subpallial boundary to the dorso-lateral part of the neopallium.
TS21: telencephalon Present Regionally restricted 1B Expression is from the pallial-subpallial boundary to the dorso-lateral part of the neopallium.

Specimen 2A,C: embryonic day 13.5 (more )
Note: 100 micron thick vibratome section. Also stained for Ncam1 (assay MGI:3576716).
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 2C , 2A Panel C is the merged image of the double-labeled section. Expression is in the intermediate zone.
TS21: cerebral cortex intermediate zone Present Regionally restricted 2A , 2C Panel C is the merged image of the double-labeled section. Expression is in the intermediate zone.

Specimen 3A,B: embryonic day 14.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Present Regionally restricted 3A , 3B Expression is in a continuous band in the intermediate zone extending from the pallial-subpallial borderline throughout the neo-and archipallium.
TS22: cortical plate Weak 3B , 3A
TS22: telencephalon ventricular layer Absent 3A , 3B
TS22: telencephalon meninges Strong 3B , 3A

Specimen 3C,D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 3C , 3D Expression is in a zone just dorsal to the pallial-subpallial borderline.
TS22: telencephalon meninges Strong 3D , 3C

Specimen Not Shown: embryonic day 15.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS23: telencephalon Present Regionally restricted Expression is in a continuous band in the intermediate zone extending from the pallial-subpallial borderline throughout the neo-and archipallium.
TS23: cerebral cortex intermediate zone Present
TS23: cortical plate Weak
TS23: telencephalon meninges Strong

Specimen 4A: embryonic day 16.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Weak 4A
TS24: telencephalon Weak Regionally restricted 4A Expression is in the deepest part of the intermediate zone as well as the narrow zone lining the pallial-subpallial boundary. Higher magnification was shown in the inset.
TS24: telencephalon meninges Strong 4A

Specimen 4B: embryonic day 17.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS25: telencephalon Weak Regionally restricted 4B Expression is in the deepest part of the intermediate zone as well as the narrow zone lining the pallial-subpallial boundary and the cortical plate of the dorsal cortex.
TS25: cerebral cortex intermediate zone Weak 4B
TS25: cortical plate Weak 4B
TS25: telencephalon meninges Strong 4B

Specimen 4C: embryonic day 18.5 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS26: cerebral cortex intermediate zone Trace 4C
TS26: cortical plate Weak Regionally restricted 4C Weak in the cortical plate of the dorsal cortex.
TS26: telencephalon meninges Strong 4C

Specimen 4D: postnatal day 1 (more )
Note: 100 micron thick vibratome section.
Structure Level Pattern Image Note
TS27: cerebral cortex Weak Regionally restricted 4D Expression is in the cortical plate of the dorsal cortex and in the ventro-lateral cortex.
TS27: meninges Strong 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory