Gene Expression Data
Assay Details
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Assay
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Reference:
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J:84446
Lioubinski O, et al., Expression of Sox transcription factors in the developing mouse pancreas. Dev Dyn. 2003 Jul;227(3):402-8
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:3582671
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Gene symbol:
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Sox8
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Gene name:
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SRY (sex determining region Y)-box 8
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
4A:
embryonic day 10.5; Sox8tm1Weg/Sox8 +
(more  )
Note: Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
Specimen
4A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Sox8tm1Weg/Sox8+
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: foregut-midgut junction |
Present |
Regionally restricted |
4A
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Expression is in scattered cells at the epithelial/mesenchymal boundary of the pancreas.
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Specimen
4B:
embryonic day 12.5; Sox8tm1Weg/Sox8 +
(more )
Note: Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
Specimen
4B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Sox8tm1Weg/Sox8+
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: pancreas |
Present |
Single cells |
4B
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Individual cells were dispersed between mesenchyme and epithelium and did not express glucagon.
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Specimen
4C:
embryonic day 18.5; Sox8tm1Weg/Sox8 +
(more )
Note: Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
Specimen
4C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Sox8tm1Weg/Sox8+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Sox8 reporter; brown - Gcg (assay MGI:3582648).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: pancreas |
Present |
Single cells |
4C
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Expressing cells are at the periphery of forming islets.
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Specimen
4D:
embryonic day 18.5; Sox8tm1Weg/Sox8 +
(more )
Note: Double labeled: blue - Sox8 reporter; brown - Ins1 (assay MGI:3582690 and Ins2 (assay MGI:3582691).
Specimen
4D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Sox8tm1Weg/Sox8+
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: blue - Sox8 reporter; brown - Ins1 (assay MGI:3582690 and Ins2 (assay MGI:3582691).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: pancreas |
Present |
Single cells |
4D
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Expressing cells are at the periphery of forming islets and did not express insulin.
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Specimen
Not Shown:
postnatal adult; Sox8tm1Weg/Sox8 +
(more )
Specimen
Not Shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Sox8tm1Weg/Sox8+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pancreas |
Present |
Single cells |
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Expressing cells are at the periphery of forming islets.
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