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Gene Expression Data
Assay Details
Assay
Reference: J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
Assay type: RNA in situ
MGI Accession ID: MGI:3585352
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: UI-M-AP0-abf-h-08-0-UI.r1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: This data is from Supplemental Table 5, Gene column, row: 134516 Otx2. After cryosectioning, tissue was fixed for 10' in 4% paraformaldehyde prior to processing.
Results
Specimen E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: neural retinal epithelium Present Regionally restricted S3_Otx2 E14 Expression was detected in the scleral outer neuroblastic layer and in a subset of cells in the vitreal outer neuroblastic layer.
Specimen E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina nuclear layer Present Regionally restricted S3_Otx2 E16 Expression was detected in the scleral outer neuroblastic layer and in a subset of cells in the vitreal outer neuroblastic layer.
Specimen E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: retina outer nuclear layer Present Regionally restricted S3_Otx2 E18 Expression was detected in the scleral outer neuroblastic layer and a subset of cells in the vitreal outer neuroblastic layer.
Specimen P0/1: postnatal day 0-1 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Weak Regionally restricted Submitted Image - U63p1.5 , S3_Otx2 P0 Expression was detected in a subset of cells in the outer neuroblastic layer.
Specimen P2/3: postnatal day 2-3 (more )
Structure Level Pattern Image Note
TS27: retina outer nuclear layer Present Regionally restricted Submitted Image - U63p3.5 , S3_Otx2 P2 Expression was detected in the vitreal outer neuroblastic layer.
Specimen P4/5: postnatal day 4-5 (more )
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted S3_Otx2 P4 Expression was detected in the vitreal outer neuroblastic layer.
Specimen P6/7: postnatal day 6-7 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Submitted Image - U63p6.5 , S3_Otx2 P6
TS28: retina outer nuclear layer Present S3_Otx2 P6 , Submitted Image - U63p6.5
Specimen P8/10: postnatal day 8-10 (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Submitted Image - U63p8.5
TS28: retina outer nuclear layer Weak Submitted Image - U63p8.5
Specimen Adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: retina Absent S3_Otx2 Adult , Submitted Image - U63adult
Specimen CNS: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present
TS28: brain subventricular zone Present
Specimen Embryo: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: olfactory epithelium Present
TS24: cerebellum Present Regionally restricted Expression was detected in cerebellum progenitors.
TS24: choroid plexus Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/03/2024
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