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Gene Expression Data
Assay Details
Assay
Reference: J:98919 Cobb J, et al., Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development. 2005 Jul;132(13):3055-67
Assay type: RNA in situ
MGI Accession ID: MGI:3689722
Gene symbol: Sgk1
Gene name: serum/glucocorticoid regulated kinase 1
Probe: Sgk cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A Wild type E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 3A Wild type E11 Expression was detected distally in forelimb bud.
Specimen 3A HoxD Del1-13 E11: embryonic day 11.0; Hoxdtm21(Hoxd11)Ddu/Hoxdtm21(Hoxd11)Ddu (more )
Structure Level Pattern Image Note
TS18: forelimb bud Absent 3A HoxD Del1-13 E11
Specimen 3A Wild type E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb interdigital region Strong Regionally restricted 3A Wild type E12.5 Expression was prominent in the proximal portion of the interdigital zone.
Specimen 3A HoxD Del1-13 E12.5: embryonic day 12.5; Hoxdtm21(Hoxd11)Ddu/Hoxdtm21(Hoxd11)Ddu (more )
Structure Level Pattern Image Note
TS20: forelimb Present Regionally restricted 3A HoxD Del1-13 E12.5 Expression was detected in the proximal forelimb of the mutant.
Specimen 3A Wild type E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb interdigital region Strong Regionally restricted 3A Wild type E13.5 Expression was prominent in the proximal portion of the interdigital zone.
Specimen 3A HoxD Del1-13 E13.5: embryonic day 13.5; Hoxdtm21(Hoxd11)Ddu/Hoxdtm21(Hoxd11)Ddu (more )
Structure Level Pattern Image Note
TS21: forelimb interdigital region Absent 3A HoxD Del1-13 E13.5
Specimen 3B Wild type E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 3B Wild type E12.5 Expression was detected in a distal domain of the ventral mesenchyme, adjacent to the urethral epithelium.
Specimen 3B HoxD Del1-13 E12.5: embryonic day 12.5; Hoxdtm21(Hoxd11)Ddu/Hoxdtm21(Hoxd11)Ddu (more )
Structure Level Pattern Image Note
TS20: genital tubercle Absent 3B HoxD Del1-13 E12.5
Specimen 3B Wild type E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: genital tubercle Present Regionally restricted 3B Wild type E13.5 Expression was detected in a distal domain of the ventral mesenchyme, adjacent to the urethral epithelium.
Specimen 3B HoxD Del1-13 E13.5: embryonic day 13.5; Hoxdtm21(Hoxd11)Ddu/Hoxdtm21(Hoxd11)Ddu (more )
Structure Level Pattern Image Note
TS21: genital tubercle Absent 3B HoxD Del1-13 E13.5
Specimen 6C Wild type: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 6C Wild type Expression was detected in digits but was not detected in the most anterior aspect of the developing distal limb.
Specimen 6C HoxD Del1-10/Del1-10: embryonic day 11.5; Del(2Hoxd1-Hoxd10)26Ddu/Del(2Hoxd1-Hoxd10)26Ddu (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 6C HoxD Del1-10/Del1-10 Expression was detected in digits and was expanded into the most anterior aspect of the developing distal limb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory