Gene Expression Data
Assay Details
Assay
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Reference:
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J:1778
Dolle P, et al., The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech Dev. 1991 Dec;36(1-2):3-13
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3767659
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Gene symbol:
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Hoxd13
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Gene name:
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homeobox D13
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Probe:
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probe A
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Probe preparation:
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Antisense labelled with S35 RNA
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Assay notes:
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Authors state that probe A (MGI:12544) was used in most experiments, but that probe B (MGI:12543) may also have been used. Both displayed the same expression patterns.
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Results
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Specimen
3A-4.8:
embryonic day 8.5
(more )
Specimen
3A-4.8:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
3B:
embryonic day 9.5
(more )
Specimen
3B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS15: embryo |
Present |
Regionally restricted |
3B
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Expression restricted to posterior areas of embryo.
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TS15: embryo mesenchyme |
Present |
Regionally restricted |
3B
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Expression widely distributed in presomitic and lateral mesoderm, neural plate and hindgut, up to the cells contacting the allantois.
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TS15: hindgut |
Present |
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3B
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Expression widely distributed in presomitic and lateral mesoderm, neural plate and hindgut, up to the cells contacting the allantois.
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TS15: tail neural plate |
Present |
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3B
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Expression widely distributed in presomitic and lateral mesoderm, neural plate and hindgut, up to the cells contacting the allantois.
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TS15: tail unsegmented mesenchyme |
Present |
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3B
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Expression widely distributed in presomitic and lateral mesoderm, neural plate and hindgut, up to the cells contacting the allantois.
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Specimen
4A:
embryonic day 11.5
(more )
Specimen
4A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
4B:
embryonic day 12.5
(more )
Specimen
4B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
5A-4.8:
embryonic day 16.5
(more )
Specimen
5A-4.8:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Female
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS24: rectum |
Present |
Regionally restricted |
5A-4.8
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Expression throughout rectum, with a sharp boundary at the rectum-anus boundary. Expression in both mesenchyme and epithelium.
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TS24: uterine horn |
Present |
Regionally restricted |
5A-4.8
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Expression in the posterior part of the uterus uterus, with a well-defined anterior boundary in the uterus.
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TS24: bladder wall |
Present |
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5A-4.8
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Specimen
not shown:
embryonic day 16.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Male
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Type:
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section
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Specimen
5B:
embryonic day 17.5
(more )
Specimen
5B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS25: rectum |
Present |
Regionally restricted |
5B
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Restricted expression in the rectum wall.
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TS25: rectum epithelium |
Present |
Regionally restricted |
5B
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Expression is more intense in the crypts of Lieberkuhn than in apical cells.
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TS25: rectum mesenchyme |
Present |
Regionally restricted |
5B
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Expression in a concentric cell layer which may correspond to the muscularis.
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Specimen
5C:
embryonic day 16.5
(more )
Specimen
5C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
6-4.8:
embryonic day 12.5
(more )
Specimen
6-4.8:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
7A:
embryonic day 9.5
(more )
Specimen
7A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS15: forelimb bud |
Weak |
Regionally restricted |
7A
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Weak expression in posterior cells of forelimb.
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Specimen
7B (left):
embryonic day 10.5
(more )
Specimen
7B (left):
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: forelimb bud |
Present |
Regionally restricted |
7B (left)
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Spatially restricted to more distal and posterior areas than Hox4.7 (Hoxd12).
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Specimen
7C (left):
embryonic day 10.5
(more )
Specimen
7C (left):
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS17: hindlimb bud |
Present |
Regionally restricted |
7C (left)
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Spatially restricted to more distal and posterior areas than Hox4.7 (Hoxd12).
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Specimen
not shown:
embryonic day 11.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
7D:
embryonic day 12.5
(more )
Specimen
7D:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS20: foot mesenchyme |
Strong |
Regionally restricted |
7D
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Strong expression in the limbs, distally restricted to footplate mesenchyme
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TS20: hand mesenchyme |
Strong |
Regionally restricted |
7D
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Strong expression in the limbs, distally restricted to footplate mesenchyme
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Specimen
7E:
embryonic day 15.5
(more )
Specimen
7E:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS23: limb |
Present |
Regionally restricted |
7E
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Authors report expression in mesenchymal cells surrounding the bone anlage.
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