About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:125993 Cankaya M, et al., An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC Genomics. 2007;8:232
Assay type: RNA in situ
MGI Accession ID: MGI:3769791
Gene symbol: Aco2
Gene name: aconitase 2, mitochondrial
Probe: MH1404 probe 1126
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 15-30 min. before further processing. A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection.
Results
Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neocortex Strong 3B Aco2
TS22: midbrain Moderate 3B Aco2
TS22: cerebellum Moderate 3B Aco2
TS22: pons Moderate 3B Aco2
TS22: medulla oblongata Strong 3B Aco2
TS22: spinal cord Strong 3B Aco2
TS22: cranial ganglion Strong 3B Aco2
TS22: dorsal root ganglion Strong 3B Aco2
TS22: olfactory epithelium Weak 3B Aco2
TS22: intestine Moderate 3B Aco2
TS22: salivary gland Strong 3B Aco2
TS22: tongue Moderate 3B Aco2
TS22: stomach Weak 3B Aco2
TS22: liver Strong 3B Aco2
TS22: lung Strong 3B Aco2
TS22: metanephros Moderate 3B Aco2
TS22: thyroid gland Moderate 3B Aco2
TS22: pituitary gland Weak 3B Aco2
TS22: pancreas Weak 3B Aco2
TS22: adrenal gland Weak 3B Aco2
TS22: heart Strong 3B Aco2
TS22: skeletal muscle Moderate 3B Aco2
TS22: cartilage Absent 3B Aco2 There is no expression in the axial cartilage.
TS22: skeleton Absent 3B Aco2 There is no expression in the long bones.
Specimen MH1404: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present MH1404_4A , MH1404_3A Expression is present in nearly all tissues.
TS22: neocortex Present MH1404_4A , MH1404_3A There is elevated expression in the marginal zone.
TS22: pons Present Regionally restricted MH1404_4A , MH1404_3A Expression is present in several pontine nuclei.
TS22: medulla oblongata Present Regionally restricted MH1404_3A , MH1404_4A Expression is present in several medullary nuclei.
TS22: spinal cord Present MH1404_3A , MH1404_4A Expression is highest in the motor columns.
TS22: dorsal root ganglion Present Non-Uniform MH1404_4A , MH1404_3A There is an intermingling of expressing and non-expressing neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory