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Gene Expression Data
Assay Details
Assay
Reference: J:125993 Cankaya M, et al., An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC Genomics. 2007;8:232
Assay type: RNA in situ
MGI Accession ID: MGI:3769792
Gene symbol: Idh2
Gene name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Probe: MH1299 probe 1068
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Cryosections of fresh frozen material were fixed in 4% paraformaldehyde for 15-30 min. before further processing. A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection.
Results
Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neocortex Moderate 3B Idh2
TS22: midbrain Moderate 3B Idh2
TS22: cerebellum Weak 3B Idh2
TS22: pons Moderate 3B Idh2
TS22: medulla oblongata Moderate 3B Idh2
TS22: spinal cord Moderate 3B Idh2
TS22: cranial ganglion Weak 3B Idh2
TS22: dorsal root ganglion Moderate 3B Idh2
TS22: olfactory epithelium Moderate 3B Idh2
TS22: intestine Strong 3B Idh2
TS22: salivary gland Moderate 3B Idh2
TS22: tongue Strong 3B Idh2
TS22: stomach Moderate 3B Idh2
TS22: liver Moderate 3B Idh2
TS22: lung Strong 3B Idh2
TS22: metanephros Moderate 3B Idh2
TS22: thyroid gland Moderate 3B Idh2
TS22: pituitary gland Moderate 3B Idh2
TS22: pancreas Strong 3B Idh2
TS22: adrenal gland Moderate 3B Idh2
TS22: heart Strong 3B Idh2
TS22: skeletal muscle Moderate 3B Idh2
TS22: cartilage Absent 3B Idh2 There is no expression in the axial cartilage.
TS22: skeleton Absent 3B Idh2 There is no expression in the long bones.
Specimen MH1299: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: embryo Present MH1299_3D , MH1299_1B There is nearly ubiquitous expression in the embryo.
TS22: choroid plexus Present MH1299_1B , MH1299_3D This is one of the tissues with the highest expression level.
TS22: heart Present MH1299_1B , MH1299_3D This is one of the tissues with the highest expression level.
TS22: lens Present MH1299_1B , MH1299_3D This is one of the tissues with the highest expression level.
TS22: skeletal muscle Present MH1299_1B , MH1299_3D This is one of the tissues with the highest expression level.
TS22: skeleton Absent MH1299_3D , MH1299_1B There is no expression in the developing axial and appendicular cartilage.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory