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Gene Expression Data
Assay Details
Assay
Reference: J:98502 Strumpf D, et al., Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3777417
Gene symbol: Nanog
Gene name: Nanog homeobox
Antibody: anti-Nanog
Detection system: Secondary antibody
Results
Specimen 5C: embryonic day 3.5 (more )
Note: This is a blastocyst.
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 5C Expression is present in the outside cells.

Specimen 5D: embryonic day 3.5; Cdx2tm1Fbe/Cdx2tm1Fbe (more )
Note: This is a blastocyst.
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 5D Expression is present in the outside cells.

Specimen 6A: embryonic day 3.0 (more )
Note: 16-cell morula.
Structure Level Pattern Image Note
TS4: compacted morula Present 6A Expression is detected in all the cells, both inner and outer cells.

Specimen Not shown: embryonic day 3.0; Cdx2tm1Fbe/Cdx2+ (more )
Note: 16-cell morula.
Structure Level Pattern Image Note
TS4: compacted morula Present Expression is detected in all the cells.

Specimen 6B: embryonic day 3.0; Cdx2tm1Fbe/Cdx2tm1Fbe (more )
Note: 16-cell morula.
Structure Level Pattern Image Note
TS4: compacted morula Present 6B Expression is detected in inner and outer cells.

Specimen 6C: embryonic day 3.25 (more )
Note: This is an early blastocyst.
Structure Level Pattern Image Note
TS4: inner cell mass Present 6C
TS4: trophectoderm Absent 6C Expression can be detected in occasional trophectoderm nuclei, but it is largely downregulated in the trophectoderm.

Specimen Not shown: embryonic day 3.25; Cdx2tm1Fbe/Cdx2+ (more )
Note: This is an early blastocyst.
Structure Level Pattern Image Note
TS4: inner cell mass Present
TS4: trophectoderm Absent

Specimen 6D: embryonic day 3.25; Cdx2tm1Fbe/Cdx2tm1Fbe (more )
Note: This is an early blastocyst.
Structure Level Pattern Image Note
TS4: inner cell mass Present 6D
TS4: trophectoderm Present 6D Expression persists in the trophectoderm cells in mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory