About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:108509 Blaess S, et al., Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809
Assay type: RNA in situ
MGI Accession ID: MGI:3810925
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe57
Probe preparation: Antisense RNA
Results
Specimen Not shown: embryonic day 8.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS13: future midbrain Absent
TS13: rhombomere 1 Absent
Specimen Not shown: embryonic day 9.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS15: future midbrain Absent
TS15: rhombomere 1 Absent
Specimen 5A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 5A Expression is present at the ventral midline.
TS15: rhombomere 1 Present Regionally restricted 5A Expression is present at the ventral midline.
TS15: diencephalon Present Regionally restricted 5A Expression is present in the ventral diencephalon.
Specimen 5B: embryonic day 9.0-9.5; Smotm2Amc/Smotm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 5B Expression is present at the ventral midline.
TS15: rhombomere 1 Present Regionally restricted 5B Expression is present at the ventral midline.
Specimen 5C: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: future midbrain Absent 5C
TS15: rhombomere 1 Absent 5C
Specimen 5C inset: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 5C inset Expression is present in the ventral diencephalon.
Specimen 5D: embryonic day 9.0-9.5; Gli2tm6Alj/Gli2tm6Alj, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 5D Expression is present at the ventral midline.
TS15: rhombomere 1 Present Regionally restricted 5D Expression is present at the ventral midline.
Specimen 5E: embryonic day 12.5; Smotm1Amc/Smotm2Amc, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5E Expression is present at the ventral midline.
TS20: midbrain Present Regionally restricted 5E Expression is present at the ventral midline.
Specimen 5E inset: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 5E inset Expression is present at the ventral midline.
TS20: midbrain Present Regionally restricted 5E inset Expression is present at the ventral midline.
Specimen S1A: embryonic day 8.5 (more )
Note: This is a horizontal section.
Structure Level Pattern Image Note
TS13: notochord Present S1_A
TS13: future midbrain Weak Regionally restricted S1_A There is weak expression in the ventral midline, overlying the notochord.
Specimen S1B: embryonic day 10.5 (more )
Note: This is a horizontal section.
Structure Level Pattern Image Note
TS17: midbrain Present S1_B Expression is present in a broad ventral domain.
Specimen S1C: embryonic day 18.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS26: midbrain Present Regionally restricted S1_C Expression is present in the ventral midline of the ventral mesencephalon.
TS26: cerebellum Present Regionally restricted S1_C Expression is present in the Purkinje cell layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory