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Gene Expression Data
Assay Details
Assay
Reference: J:145440 Romand R, et al., Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear. J Comp Neurol. 2006 Jun 10;496(5):643-54
Assay type: RNA in situ
MGI Accession ID: MGI:3841155
Gene symbol: Cyp26a1
Gene name: cytochrome P450, family 26, subfamily a, polypeptide 1
Probe: Cyp26a1 probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst mesenchyme Strong Regionally restricted 5D Strong expression was detected in the mesenchymal tissues surrounding the lateral and ventral domains of the otocyst.
TS17: otocyst epithelium Strong Regionally restricted 5D Strong expression was detected in the ventral otic epithelium that gives rise to the cochlear epithelium.
TS17: acoustic ganglion Absent 5D

Specimen 5I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear Present Regionally restricted 5I Expression was strong in the ventral region of the otocyst.
TS20: semicircular canal mesenchyme Strong Regionally restricted 5I Expression was strong in the mesenchyme surrounding all semicircular canals.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present
TS22: endolymphatic duct Present
TS22: inner ear Present Regionally restricted Expression was detected in the endolymphatic duct, the tissues surrounding the round window membrane, and beneath the sensory epithelium in the sacculus.
TS22: saccule Present Regionally restricted Expression was detected beneath the sensory epithelium in the sacculus.

Specimen 5N: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea Present 5N
TS22: inner ear vestibular component Present Regionally restricted 5N Expression was detected below the sensory epithelium of the saccule, presumably in vestibular ganglion cells.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: endolymphatic duct Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory