Gene Expression Data
Assay Details
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Assay
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Reference:
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J:112945
Okubo T, et al., Sox2 is required for development of taste bud sensory cells. Genes Dev. 2006 Oct 1;20(19):2654-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:4834770
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Gene symbol:
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Sox2
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Gene name:
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SRY (sex determining region Y)-box 2
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Results
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Specimen
1D:
embryonic day 15.5
(more  )
Specimen
1D:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
S2J:
embryonic day 16.5
(more )
Specimen
S2J:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
S2K:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Sox2tm1Lpev/Sox2tm3Lpev
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: fungiform papillae |
Trace |
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S2K
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Expression was detected in the fungiform papillae, but there were far fewer fungiform papillae in the mutants compared to wild type.
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| TS24: tongue epithelium |
Trace |
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S2K
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Expression was reduced in the epithelium.
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Specimen
S2L:
embryonic day 18.5
(more )
Specimen
S2L:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
S2M:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Sox2tm1Lpev/Sox2tm3Lpev
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: fungiform papillae |
Absent |
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S2M
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The fungiform papillae are no longer morphologically detected in the mutants compared to wild type at E18.5.
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Specimen
2G:
postnatal day 0
(more )
Specimen
2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: tongue |
Present |
Regionally restricted |
2G
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Expression was detected in the fungiform papillae and the basal layer of keratinocytes.
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| TS27: fungiform papillae |
Present |
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2G
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Specimen
2H:
(close )
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Genetic Background:
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involves: 129S/SvEv
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Mutant Allele(s):
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Sox2tm1Lpev/Sox2tm3Lpev
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: tongue |
Weak |
Regionally restricted |
2H
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Expression was weak in the basal layer of keratinocytes, and the mutant tongue had no fungiform papillae.
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| TS27: fungiform papillae |
Absent |
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2H
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The mutant tongue had no fungiform papillae.
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Specimen
3B:
embryonic day 18.5
(more )
Specimen
3B:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Analysis Tools