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Gene Expression Data
Assay Details
Assay
Reference: J:150086 Kiso M, et al., The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9292-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4844118
Gene symbol: Sox21
Gene name: SRY (sex determining region Y)-box 21
Antibody: Anti-Sox21
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt14 (assay MGI:4844111).
Structure Level Pattern Image Note
TS28: hair follicle Strong Regionally restricted 2D Expression was detected along the hair shaft.
TS28: hair outer root sheath Absent 2D
Specimen 2E: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt71 (assay MGI:4844112).
Structure Level Pattern Image Note
TS28: hair follicle Strong Regionally restricted 2E Expression was detected along the hair shaft.
TS28: hair inner root sheath Absent 2E
Specimen 2F & F'': postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt32 (assay MGI:4844113).
Structure Level Pattern Image Note
TS28: hair cuticle Present 2F'' , 2F
Specimen 2G & G'': postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt31 (assay MGI:4844116).
Structure Level Pattern Image Note
TS28: hair cuticle Present 2G , 2G''
Specimen 2H & H'': postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Pcna (assay MGI:4844114).
Structure Level Pattern Image Note
TS28: dermis papillary layer Present Regionally restricted 2H , 2H'' Expression was detected in the proximal postmitotic cells.
Specimen S3A Filaggrin/Sox21: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Flg (assay MGI:4844139).
Structure Level Pattern Image Note
TS28: epidermis Weak Regionally restricted S3A Filaggrin/Sox21 Weak expression was detected in the infundibulum and interfollicular epidermis.
Specimen S3A K10/Sox21: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt10 (assay MGI:4844140).
Structure Level Pattern Image Note
TS28: epidermis Weak Regionally restricted S3A K10/Sox21 Weak expression was detected in the infundibulum and interfollicular epidermis.
Specimen S3A K14/Sox21: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Krt14 (assay MGI:4844111).
Structure Level Pattern Image Note
TS28: epidermis Weak Regionally restricted S3A K14/Sox21 Weak expression was detected in the infundibulum and interfollicular epidermis.
Specimen S3A PCNA/Sox21: postnatal day 5 (more )
Note: Double labeled: green - Sox21; red - Pcna (assay MGI:4844114).
Structure Level Pattern Image Note
TS28: epidermis Weak Regionally restricted S3A PCNA/Sox21 Weak expression was detected in the infundibulum and interfollicular epidermis.
Specimen S3C P7: postnatal day 7 (more )
Note: Anagen phase.
Structure Level Pattern Image Note
TS28: hair follicle Strong S3C Sox21+/+ P7 Strong expression was detected in the anagen-stage hair follicle.
TS28: epidermis Present S3C Sox21+/+ P7 inset , S3C Sox21+/+ P7
Specimen S3C P15: postnatal day 15 (more )
Note: Catagen.
Structure Level Pattern Image Note
TS28: hair follicle Present S3C Sox21+/+ P15
TS28: epidermis Present S3C Sox21+/+ P15 , S3C Sox21+/+ P15 inset
Specimen S3C P19: postnatal day 19 (more )
Note: Telogen phase.
Structure Level Pattern Image Note
TS28: hair follicle Absent S3C Sox21+/+ P19 Expression became undetectable in telogen stage as hair follicles regressed.
TS28: epidermis Present S3C Sox21+/+ P19 , S3C Sox21+/+ P19 inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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