Gene Expression Data
Assay Details
Assay
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Reference:
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J:74240
Mui SH, et al., The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development. 2002 Feb;129(3):797-804
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5298351
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Gene symbol:
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Foxg1
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Gene name:
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forkhead box G1
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Probe:
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BF1 probe4
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Probe preparation:
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Antisense labelled with P33 RNA
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Results
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Specimen
4G +/-:
embryonic day 16.5; Vax2tm1Grl/Vax2 +
(more )
Specimen
4G +/-:
(close )
Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Vax2tm1Grl/Vax2+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS24: retina |
Present |
Graded |
4G +/-
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Expression was detected preferentially in the nasal as opposed to the temporal side of the eye.
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Specimen
4G -/-:
(close )
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Vax2tm1Grl/Vax2tm1Grl
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: retina |
Present |
Graded |
4G -/-
|
Expression was unaltered in the mutant compared to the wild type. Express was detected preferentially in the nasal as opposed to the temporal side of the eye.
|
Specimen
not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Vax2tm1Grl/Vax2tm1Grl
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: optic cup |
Present |
|
|
Expression domain in the retina was unaffected in the mutant.
|
Specimen
not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Vax2tm1Grl/Vax2tm1Grl
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Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: retina |
Present |
Regionally restricted |
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The expression domain in the dorsal nasal retina was unaffected in the mutant.
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Specimen
not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
Mutant Allele(s):
|
Vax2tm1Grl/Vax2tm1Grl
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Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: retina |
Present |
|
|
Expression domain was unaffected in the mutant.
|
Specimen
not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * C57BL/6
|
Mutant Allele(s):
|
Vax2tm1Grl/Vax2tm1Grl
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Age:
|
postnatal day 0
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: retina |
Present |
|
|
Expression domain was unaffected in the mutant.
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