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Gene Expression Data
Assay Details
Assay
Reference: J:79392 Bai CB, et al., Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development. 2002 Oct;129(20):4753-61
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5320630
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Reporter: lacZ
Direct Detection
Results
Specimen 3E: embryonic day 7.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS11: embryo Weak Regionally restricted 3E Expression is present close to the midline in the head process.

Specimen 3F: embryonic day 8.0; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 3F Expression is present in the area surrounding the node.

Specimen 3G: embryonic day 8.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS13: embryo mesenchyme Present Regionally restricted 3G Expression is detected in mesodermal cells surrounding the notochord.
TS13: embryo Present Regionally restricted 3G Expression is present cells next to the floor plate.
TS13: gut Present 3G

Specimen 3H: embryonic day 9.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS15: embryo mesenchyme Present Regionally restricted 3H Expression is detected in mesodermal cells surrounding the notochord.
TS15: embryo Present Regionally restricted 3H Expression is present cells next to the floor plate.
TS15: gut Present 3H

Specimen 3O: embryonic day 8.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 3O Expression is present in the ventral central nervous system.
TS13: embryo mesenchyme Present Regionally restricted 3O Expression is present in some mesodermal cells surrounding the notochord.
TS13: gut Present 3O

Specimen 3P: embryonic day 8.5; Gli1tm2Alj/Gli1+, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS13: gut Weak 3P
TS13: embryo mesenchyme Present Regionally restricted 3P Expression in the mesodermal cells sourrounding the notochord is greatly reduced.
TS13: neural ectoderm Absent 3P There is no expression in the ventral central nervous system.

Specimen 3Q: embryonic day 10.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS17: central nervous system Strong Regionally restricted 3Q Expression is present in the ventral central nervous system.
TS17: gut Strong 3Q
TS17: forelimb bud Strong Regionally restricted 3Q Expression is present in the posterior limb bud.

Specimen 3R: embryonic day 10.5; Gli1tm2Alj/Gli1+, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: central nervous system Absent 3R
TS17: forelimb bud Absent 3R
TS17: gut Present 3R


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory