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Gene Expression Data
Assay Details
Assay
Reference: J:29934 Williams R, et al., Complementary and combinatorial patterns of Notch gene family expression during early mouse development. Mech Dev. 1995 Nov;53(3):357-68
Assay type: RNA in situ
MGI Accession ID: MGI:5433852
Gene symbol: Notch1
Gene name: notch 1
Probe: Notch1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo Present Regionally restricted 1A Expression is in the notochord.

Specimen 1E: embryonic day 7.5-8.0 (more )
Structure Level Pattern Image Note
TS11: blood island Present 1E
TS11: embryo mesoderm Present Regionally restricted 1E Expression is just anterior to the node and within cells of the posterior mesoderm.

Specimen 2 upper: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: notochordal plate Present 2_upper
TS11: embryo mesoderm Present Regionally restricted 2_upper Expression is in isolated groups of cells withing the splanchnic mesoderm.
TS11: neural fold Present Regionally restricted 2_upper Expression is ventral.
TS11: mesenchyme derived from head mesoderm Weak 2_upper

Specimen 3A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: trunk unsegmented mesenchyme Strong Regionally restricted 3A At the anterior limit of the streak just caudal to the most recently formed somite.
TS12: somite Strong Regionally restricted 3A Expression is in the dorso-medial region.
TS12: endocardial tube Present 3A

Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present Regionally restricted 4A Expression is in the epibranchial placodes.
TS15: otic pit Present 4A
TS15: trigeminal preganglion Present 4A
TS15: otocyst Present Regionally restricted 4A Expression is ventral and in a few cells more caudal.
TS15: diencephalon Present 4A
TS15: future forebrain Strong Regionally restricted 4A Expression is in the region separating the ventral telencephalon and the otpic stalk.
TS15: cranial preganglion Present Regionally restricted 4A Expression is in the lateral margins of the newly formed ganglia.

Specimen 4D: embryonic day 9.5 (more )
Note: Section taken through the maxillary and mandibular components of the first branchial arch, the second branchial arch and the fourth ventricle.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 4D
TS15: olfactory placode Present 4D

Specimen 4E: embryonic day 9.5 (more )
Note: Section through part of the third branchial arch and the otic vesicle.
Structure Level Pattern Image Note
TS15: 3rd branchial arch mesenchyme derived from neural crest Present Regionally restricted 4E Expression was detected within the third epibranchial placode and also within placode-derived cells that have begun migrating to the site of the vestibuloacoustic (VII/VIII) ganglion anlage.
TS15: facio-acoustic preganglion complex Present Regionally restricted 4E Expression was detected within the third epibranchial placode and also within placode-derived cells that have begun migrating to the site of the vestibuloacoustic (VII/VIII) ganglion anlage.

Specimen 5A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 5A
TS17: neural tube roof plate Present 5A
TS17: somite Weak 5A

Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye mesenchyme Present Regionally restricted 5D Expression is between the surface and lens epithelium.
TS17: peripheral nerve trunk Absent 5D


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory