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Gene Expression Data
Assay Details
Assay
Reference: J:83659 Wright TJ, et al., Fgf3 and Fgf10 are required for mouse otic placode induction. Development. 2003 Aug;130(15):3379-90
Assay type: RNA in situ
MGI Accession ID: MGI:5435911
Gene symbol: Pax2
Gene name: paired box 2
Probe: Pax2 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Not shown: embryonic day 8.0 (more )
Note: 2-8 somite-stage embryo.
Structure Level Pattern Image Note
TS12: otic placode epithelium Present Expression is present in the presumptive otic ectoderm.
Specimen 3E: embryonic day 9.5; Fgf3tm1Mrc/Fgf3+ (more )
Structure Level Pattern Image Note
TS15: otocyst Present 3E
TS15: eye Present 3E
TS15: midbrain-hindbrain junction Present 3E
TS15: genitourinary system Present Regionally restricted 3E Expression is present in the kidney.
Specimen 3F: embryonic day 9.5; Fgf3tm1Mrc/Fgf3+ (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 3F Expression is present in the ventromedial wall.
Specimen 3G: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Structure Level Pattern Image Note
TS15: otocyst Absent 3G Expression was lacking in the otic region, even when the double mutants appeared to have microvesicles.
TS15: eye Present 3G
TS15: midbrain-hindbrain junction Present 3G
TS15: genitourinary system Present Regionally restricted 3G Expression is present in the kidney.
Specimen 3H: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Absent 3H Expression was lacking in the otic region, even when the double mutants appeared to have microvesicles.
Specimen 4A: embryonic day 8.5; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10+ (more )
Note: Eight somite-stage embryo.
Structure Level Pattern Image Note
TS13: otic placode epithelium Present 4A Expression is present in the otic ectoderm.
TS13: eye Present 4A
TS13: midbrain-hindbrain junction Present 4A
TS13: genitourinary system Present Regionally restricted 4A Expression is present in the kidney.
Specimen 4B: embryonic day 8.5; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10+ (more )
Note: Eight somite-stage embryo. This section is through the otic region.
Structure Level Pattern Image Note
TS13: otic placode epithelium Present 4B Expression is present in the otic ectoderm.
Specimen 4C: embryonic day 8.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: Eight somite-stage embryo.
Structure Level Pattern Image Note
TS13: otic placode Absent 4C There is no expression in the otic region.
TS13: eye Present 4C
TS13: midbrain-hindbrain junction Present 4C
TS13: genitourinary system Present Regionally restricted 4C Expression is present in the kidney.
Specimen 4D: embryonic day 8.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: Eight somite-stage embryo. This section is through the otic region.
Structure Level Pattern Image Note
TS13: otic placode Absent 4D There is no expression in the otic region.
Specimen 6A: embryonic day 9.5; Fgf10tm1Wss/Fgf10tm1Wss (more )
Structure Level Pattern Image Note
TS15: otocyst Present 6A
Specimen 6B: embryonic day 9.5; Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 6B Expression is present in the ventromedial wall.
Specimen 6C: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc (more )
Structure Level Pattern Image Note
TS15: otocyst Present 6C The size and the location of the otic vesicles are variably altered in the mutants.
Specimen 6D: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 6D Expression is present in the ventromedial wall. The size and the location of the otic vesicles are variably altered in the mutants.
Specimen 6E: embryonic day 9.5; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10tm1Wss (more )
Structure Level Pattern Image Note
TS15: otocyst Present 6E According to one measurement, otic vesicles in the mutants are only 72% of the size of those in controls.
Specimen 6F: embryonic day 9.5; Fgf3tm1Mrc/Fgf3+, Fgf10tm1Wss/Fgf10tm1Wss (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 6F Expression is present in the ventromedial wall. According to one measurement, otic vesicles in the mutants are only 72% of the size of those in controls.
Specimen 6G: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10+ (more )
Structure Level Pattern Image Note
TS15: otocyst Present 6G Expression is expanded dorsally and laterally in the mutant. In addition, according to one measurement, otic vesicles in the mutants are only 47% of the size of those in controls.
Specimen 6H: embryonic day 9.5; Fgf3tm1Mrc/Fgf3tm1Mrc, Fgf10tm1Wss/Fgf10+ (more )
Note: This section is through the otic region.
Structure Level Pattern Image Note
TS15: otocyst Present Regionally restricted 6H Expression is expanded dorsally and laterally in the mutant. In addition, according to one measurement, otic vesicles in the mutants are only 47% of the size of those in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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