Gene Expression Data
Assay Details
Assay
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Reference:
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J:51386
Stanley E, et al., DAN is a secreted glycoprotein related to Xenopus cerberus. Mech Dev. 1998 Oct;77(2):173-84
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5444519
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Gene symbol:
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Nbl1
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Gene name:
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NBL1, DAN family BMP antagonist
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Probe:
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Dan probe3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Assay notes:
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It was possible that Dan probe4 (MGI:5444517) was also used.
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Results
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Specimen
not shown:
embryonic day 6.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 6.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
not shown:
embryonic day 8.0
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
5A:
embryonic day 8.5
(more )
Specimen
5A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: embryo |
Present |
Regionally restricted |
5A
|
Expression first apparent around E8.5.
|
TS13: head mesenchyme |
Present |
Regionally restricted |
5A
|
Expression in head mesenchyme ventral to midbrain.
|
TS13: head somite |
Present |
Regionally restricted |
5A
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Expression in nascent somites, in 2 or more stripes.
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Specimen
5B:
embryonic day 9.5
(more )
Specimen
5B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
5C:
embryonic day 10.5
(more )
Specimen
5C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: somite |
Present |
|
5C
|
Expression throughout the somite array.
|
TS17: forelimb bud |
Present |
Regionally restricted |
5C
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Expression in dorsoanterior aspect of forelimb bud.
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Specimen
5D:
embryonic day 10.5
(more )
Specimen
5D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
5E:
embryonic day 12.5
(more )
Specimen
5E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
5F:
embryonic day 12.5
(more )
Specimen
5F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: head mesenchyme |
Present |
Regionally restricted |
5F
|
High expresssion in facial primordia.
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Specimen
6A:
embryonic day 9.5
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: somite |
Present |
Regionally restricted |
6A
|
Expression predominantly localized to caudal region of most recently formed somite.
|
TS15: tail unsegmented mesenchyme |
Weak |
Regionally restricted |
6A
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Weaker expression in a stripe within presomitic mesoderm.
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Specimen
6B:
embryonic day 9.5
(more )
Specimen
6B:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: somite |
Present |
Regionally restricted |
6B
|
Expression within presomitic mesoderm and nascent somites most prominent in a zone adjacent to the neural tube.
|
TS15: tail unsegmented mesenchyme |
Present |
Regionally restricted |
6B
|
Expression within presomitic mesoderm and nascent somites most prominent in a zone adjacent to the neural tube.
|
Specimen
6C:
embryonic day 9.5
(more )
Specimen
6C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: somite |
Present |
Regionally restricted |
6C
|
In epithelial somites re-initiating expression, expression localized approximately centrally (confined to medial half) within somite boundaries and adjacent to the neural tube.
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Specimen
6D:
embryonic day 9.5
(more )
Specimen
6D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: sclerotome |
Present |
Regionally restricted |
6D
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In older somites, expression predominantly restricted to medial part of sclerotome proximal to neural tube.
|
TS15: dermomyotome |
Absent |
|
6D
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No expression in dorsal lip of dermomyotome.
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Specimen
6E:
embryonic day 12.5
(more )
Specimen
6E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: sclerotome |
Present |
Regionally restricted |
6E
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As somites mature, expression becomes progressively restricted. No expression except in caudal-most segments.
|
TS20: myotome |
Present |
Regionally restricted |
6E
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Expression predominantly in developing myotomes, with no apparent restriction along the antero-posterior axis.
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Specimen
6F:
embryonic day 12.5
(more )
Specimen
6F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: forelimb mesenchyme |
Present |
Regionally restricted |
6F
|
Subepithelial expression in dorsal and ventral domains.
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Specimen
6G:
embryonic day 10.5
(more )
Specimen
6G:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
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Specimen
6H:
embryonic day 10.5
(more )
Specimen
6H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Specimen
6I:
embryonic day 12.5
(more )
Specimen
6I:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: head mesenchyme |
Present |
Regionally restricted |
6I
|
Subepithelial mesenchymal expression in facial primordia.
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Specimen
7A:
embryonic day 11.0; Myf5tm1Pas/Myf5 +
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
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Mutant Allele(s):
|
Myf5tm1Pas/Myf5+
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Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
7B:
embryonic day 11.0; Myf5tm1Pas/Myf5 +
(more )
Specimen
7B:
(close )
Genetic Background:
|
Not Specified
|
Mutant Allele(s):
|
Myf5tm1Pas/Myf5+
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Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
not shown:
embryonic day 11.0
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Specimen
7C:
embryonic day 12.5
(more )
Specimen
7C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Specimen
7D:
(close )
Genetic Background:
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C57BL/6J-Pax3Sp/J
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Mutant Allele(s):
|
Pax3Sp/Pax3Sp
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Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: limb mesenchyme |
Present |
|
7D
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No difference in expression pattern compared to wild type embryos.
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