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Gene Expression Data
Assay Details
Assay
Reference: J:75699 Albrecht AN, et al., The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
Assay type: RNA in situ
MGI Accession ID: MGI:5446452
Gene symbol: Hoxd11
Gene name: homeobox D11
Probe: Hoxd11 probe18
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown 10.5 wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted
Specimen not shown 10.5 spdh/spdh: embryonic day 10.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted Authors report normal expression domains with respect to anterior and posterior borders, but with reduced overall area of expression compared with wildtype.
Specimen 2 Hoxd11 11.5 wt: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 2_Hoxd11 11.5 wt/wt
Specimen 2 Hoxd11 11.5 spdh/spdh: embryonic day 11.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS19: handplate Present Regionally restricted 2_Hoxd11 11.5 spdh/spdh Reduced expression domain with normal anterior and posterior borders
Specimen 2 Hoxd11 12.5 wt: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2_Hoxd11 12.5 wt/wt Expression in perichondrium and presumptive joint regions of these digits.
Specimen 2 Hoxd11 12.5 spdh/spdh: embryonic day 12.5; Hoxd13spdh/Hoxd13spdh (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 2_Hoxd11 12.5 spdh/spdh Reduced expression domain with normal anterior and posterior borders.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory