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Gene Expression Data
Assay Details
Assay
Reference: J:57820 Ferguson C, et al., Does adult fracture repair recapitulate embryonic skeletal formation?. Mech Dev. 1999 Sep;87(1-2):57-66
Assay type: RNA in situ
MGI Accession ID: MGI:5447314
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: ihh probe13
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A ihh: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: humerus pre-cartilage condensation Present 1A ihh

Specimen 1B ihh/gli1: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 1B ihh/gli1 Expression restricted to chondrocytes in humerus, radius and ulna, and in mesenchymal cells of digits.
TS21: radius-ulna cartilage condensation Present 1B ihh/gli1 Expression restricted to chondrocytes in humerus, radius and ulna, and in mesenchymal cells of digits.
TS21: forelimb digit mesenchyme Present 1B ihh/gli1 Expression restricted to chondrocytes in humerus, radius and ulna, and in mesenchymal cells of digits.

Specimen 1C ihh: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb cartilage condensation Present Regionally restricted 1C ihh Expression restricted to mature and early hypertrophic chondrocytes.

Specimen 2A ihh: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: forelimb skeleton Strong Regionally restricted 2A ihh Expression restricted to mature and early hypertrophic chondrocytes.

Specimen 2D ihh: postnatal week 10 (more )
Structure Level Pattern Image Note
TS28: tibia Weak Regionally restricted 2D ihh Very low levels of expression detected in secondary ossification center.
TS28: long bone epiphyseal plate hypertrophic zone Present Regionally restricted 2D ihh Expression restricted to mature and early hypertrophic chondrocytes of the growth plate.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory