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Gene Expression Data
Assay Details
Assay
Reference: J:155881 Bedogni F, et al., Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology. Gene Expr Patterns. 2010 Jan;10(1):9-15
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5448651
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3A/a: embryonic day 13.0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS21: cerebral cortex Present 3a , 3A Expressed in postmitotic neurons.
Specimen 3E/e: embryonic day 14.0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Weak 3E , 3e Expressed in migrating cells.
TS22: cortical plate Present 3e , 3E
Specimen 3G: postnatal day 0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS27: cortical layer VI Present 3G Expressed mostly in layer 6.
Specimen 3L: postnatal day 21 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS28: cerebral cortex Present 3L Present in cortical neurons.
Specimen 4B: postnatal day 0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS27: dentate gyrus Present 4B
TS27: hippocampus region Present 4B
Specimen 5A/a: embryonic day 14.0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS22: cerebellum Present Regionally restricted 5A , 5a High expression in the nuclear transitory zone.
Specimen 5B: postnatal day 21 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS28: deep cerebellar nucleus Present 5B
Specimen 5C: embryonic day 14.0 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS22: thalamus Present Regionally restricted 5C Expressed in the eminentia thalami.
Specimen 5D: postnatal day 21 (more )
Note: Double labeled: red - Tbr1; green - Auts2 (assay MGI:5448185).
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 5D Expressed in the periglomerular cells.
TS28: main olfactory bulb mitral cell layer Present 5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory