About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:43772 Pattyn A, et al., Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development. 1997 Oct;124(20):4065-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5463996
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Antibody: anti-Phox2b
Results
Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 2E Expression in presumptive facial motoneurons at the level of r4, undergoing caudal migration through r5. Expression in neuroepithelium of r4, but not of r5. Expression in lateral/dorsally migrating cells in r6.

Specimen 3A: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: area postrema Present 3A
TS27: dorsal motor nucleus of vagus nerve Present 3A
TS27: solitary tract nucleus Present 3A

Specimen 3C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: nucleus ambiguus Present 3C

Specimen 3D: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: facial nucleus Present 3D

Specimen 3E: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: medulla oblongata Present Regionally restricted 3E Expression in A1/C1 (nor)adrenergic groups in the ventrolateral medulla.

Specimen 3F: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: medulla oblongata Present Regionally restricted 3F Expression in A2/C2 (nor)adrenergic groups in the dorsomedial aspect of the medulla.

Specimen not shown: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: oculomotor nucleus Present
TS27: trochlear nucleus Present
TS27: spinal cord Absent

Specimen 5D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Weak Regionally restricted 5D Expression in the metencephalon. low levels of expression in the caudal aspect of the trochlear (IV) nucleus.
TS15: rhombomere 1 Absent 5D No expression in locus coeruleus precursors.

Specimen 5F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present Regionally restricted 5F Expression in the isthmus at the level of the oculomotor (III) nucleus. Expression only in postmitotic neurons of the mantle layer.

Specimen 5H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 5H Expression in the rhombencephalon at the level of rhombomere 4.
TS17: rhombomere 4 mantle layer Present Regionally restricted 5H Expression in the mantle layer at the level of the ventral and lateral columns.
TS17: rhombomere 4 ventricular layer Present 5H

Specimen 7B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: peripheral nervous system Present Regionally restricted 7B Expression in enteric neuroblasts invading the gut.

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: peripheral nervous system Present Regionally restricted Expression in a few cells lateral to the aorta at thoracic levels, corresponding to the earliest sympathetic neuroblasts.

Specimen 7D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: glossopharyngeal ganglion Present Regionally restricted 7D Expression in epibranchial placodes of the distal IXth and Xth cranial ganglia, before delamination of neuroblasts.
TS17: vagus ganglion Present Regionally restricted 7D Expression in epibranchial placodes of the distal IXth and Xth cranial ganglia, before delamination of neuroblasts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory