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Gene Expression Data
Assay Details
Assay
Reference: J:135686 Hirashima M, et al., Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol. 2008 Apr 1;316(1):149-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5476686
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: Anti-Prox1 (PRB-238C; Poly19252)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6A: embryonic day 11.5 (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:5476631).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 6A Expression was detected in a lymphatic endothelial cell population at the dorsolateral part of the cardinal vein.
TS19: lymphatic system Present Regionally restricted 6A Expression was detected in a lymphatic endothelial cell population at the dorsolateral part of the cardinal vein.

Specimen 6B: embryonic day 11.5; Ppp1r13btm1Suda/Ppp1r13btm1Suda (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:5476631).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 6B Expression was detected in a lymphatic endothelial cell population at the dorsolateral part of the cardinal vein as in wild type.
TS19: lymphatic system Present Regionally restricted 6B Expression was detected in a lymphatic endothelial cell population at the dorsolateral part of the cardinal vein as in wild type.

Specimen 6D +/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 6D +/+ Expression was detected in lymphatic endothelial cells. Data was presented in a graph of the number of immunopositive nuclei.

Specimen 6D -/-: embryonic day 14.5; Ppp1r13btm1Suda/Ppp1r13btm1Suda (more )
Structure Level Pattern Image Note
TS22: lymphatic system Present Regionally restricted 6D -/- Expression was detected in lymphatic endothelial cells. Data was presented in a graph of the number of immunopositive nuclei. The number of immunopositive cells was normal in the mutant embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory