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Gene Expression Data
Assay Details
Assay
Reference: J:14821 Ng LJ, et al., Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev Biol. 1993 Oct;159(2):403-17
Assay type: RNA in situ
MGI Accession ID: MGI:5490272
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: pEL111
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probe detects boty type IIA and IIB transcripts.
Results
Specimen 5D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vertebral cartilage condensation Present Uniform 5D Uniform pattern of expression in entire mesenchymal population of developing vertebral bodies.

Specimen 5F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vertebra Present Widespread 5F Expression in all chondrocytes including hypertrophic chondrocytes in the core of cartilage.

Specimen 5H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vertebra Present Uniform 5H

Specimen 6B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: chondrocranium Present Ubiquitous 6B Ubiquitous expression in cartilage of neurocranium and cervical vertebrae.
TS23: vertebra Present Ubiquitous 6B Ubiquitous expression in cartilage of neurocranium and cervical vertebrae.

Specimen 6F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: otic capsule Strong Widespread 6F Widespread pattern of expression in cartilagnous otic capsule and supro-occipital cartilage.
TS26: otic cartilage Strong Widespread 6F Widespread pattern of expression in cartilagnous otic capsule and supro-occipital cartilage.
TS26: inner ear epithelium Present 6F Expression in sensory and secretory epithelia of the inner ear.

Specimen 6I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: chondrocranium Strong Regionally restricted 6I Strong level of expression in calvarial mesenchyme.
TS24: diencephalon ventricular layer Strong 6I
TS24: midbrain ventricular layer Strong 6I

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present

Specimen not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present

Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Strong Strong expression in mesenchymal condensation of Meckel's cartilage and later in the cartilage.
TS21: limb mesenchyme Present
TS21: tail sclerotome Present Regionally restricted Uniform expression in medial sclerotomal cells.

Specimen not shown E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: Meckel's cartilage Strong Uniform
TS22: rib cartilage condensation Present Widespread Expression in entire chondrocyte population of developing ribs.

Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: Meckel's cartilage Strong Uniform
TS23: rib Present Widespread Expression in entire chondrocyte population of developing ribs.

Specimen not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory