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Gene Expression Data
Assay Details
Assay
Reference: J:144758 Ho HY, et al., Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells. Mech Dev. 2009 Jan-Feb;126(1-2):18-29
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5496201
Gene symbol: Pitx3
Gene name: paired-like homeodomain transcription factor 3
Reporter: GFP
Direct Detection
Results
Specimen 1A: embryonic day 10.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS17: lens pit Present 1A
Specimen 1B: embryonic day 11.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present Regionally restricted 1B Expression is in the lens epithelium and differentiating primary fiber cells.
Specimen 1C: embryonic day 12.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present 1C
TS20: lens vesicle Present Regionally restricted 1C Expression is in differentiating primary fiber cells.
Specimen 1D: embryonic day 10.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS17: lens pit Present 1D
Specimen 1E: embryonic day 11.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 1E The mutant lens is smaller and lacks a regular spherical geometry in comparison with wild-type and heterozygous littermates.
Specimen 1F: embryonic day 12.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present 1F The mutant eye contains a rudimentary lens consisting of disorganized cells.
Specimen 1G: embryonic day 11.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 1G
Specimen 1H: embryonic day 11.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 1H This mutant has an irregular shape and smaller size lens.
Specimen 4B: embryonic day 10.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS17: lens pit Present 4B
Specimen 4D: embryonic day 10.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS17: lens pit Present 4D
Specimen 4F: embryonic day 11.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 4F
Specimen 4H: embryonic day 11.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 4H
Specimen 4J: embryonic day 10.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS17: lens pit Present 4J
Specimen 4L: embryonic day 10.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS17: lens pit Present 4L
Specimen 4N: embryonic day 11.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 4N
Specimen 4P: embryonic day 11.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 4P
Specimen 4R: embryonic day 12.5; Pitx3tm1Mli/Pitx3+ (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 4R
Specimen 4T: embryonic day 12.5; Pitx3tm1Mli/Pitx3tm1Mli (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 4T
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory