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Gene Expression Data
Assay Details
Assay
Reference: J:70279 Garg V, et al., Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev Biol. 2001 Jul 1;235(1):62-73
Assay type: RNA in situ
MGI Accession ID: MGI:5502546
Gene symbol: Tbx1
Gene name: T-box 1
Probe: Tbx1 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present 2B Expressed in the pharyngeal arches.
TS15: otic pit Present Regionally restricted 2B Expressed in the ventral half.
TS15: head Present 2B
Specimen 2C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 2C Expressed in the mesodermal core of pharyngeal arches.
TS15: trunk mesenchyme Present Regionally restricted 2C Expressed in periaortic mesenchyme.
Specimen 4A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch mesenchyme Present Regionally restricted 4A , 4B Expressed in the mesodermal core.
TS17: otocyst Present 4B , 4A Expressed in the otic vesicle.
TS17: trunk mesenchyme Present Regionally restricted 4A , 4B Expressed in periaortic mesenchyme.
Specimen 4E/F: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: branchial arch mesenchyme Present Regionally restricted 4F , 4E Decreased expression in the mesodermal core, compared with the wild type.
TS17: otocyst Present 4F , 4E Expressed in the otic vesicle, same as the wild type.
TS17: trunk mesenchyme Present Regionally restricted 4E , 4F Expressed in periaortic mesenchyme, same as the wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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