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Gene Expression Data
Assay Details
Assay
Reference: J:71389 Manley NR, et al., Hoxb2 and hoxb4 act together to specify ventral body wall formation. Dev Biol. 2001 Sep 1;237(1):130-44
Assay type: RNA in situ
MGI Accession ID: MGI:5505794
Gene symbol: Alx3
Gene name: aristaless-like homeobox 3
Probe: Alx3 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7F: embryonic day 11.0; Hoxb4tm1Nrm/Hoxb4+ (more )
Structure Level Pattern Image Note
TS18: branchial arch Present 7F
TS18: trunk mesenchyme derived from neural crest Present 7F
TS18: body wall Present Regionally restricted 7F Expression was detected in the ventral body wall.
TS18: trunk mesenchyme Present Regionally restricted 7F Expression was detected in lateral plate mesoderm and flank mesoderm.

Specimen 7G: embryonic day 11.0; Hoxb4tm1Nrm/Hoxb4tm1Nrm (more )
Structure Level Pattern Image Note
TS18: body wall Present 7G Expression appears similar to the control.
TS18: branchial arch Present 7G Expression appears similar to the control.
TS18: trunk mesenchyme Present 7G Expression appears similar to the control.
TS18: trunk mesenchyme derived from neural crest Present 7G Expression appears similar to the control.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present

Specimen not shown: embryonic day 10.5; Hoxb2tm1Mrc/Hoxb2tm1Mrc (more )
Structure Level Pattern Image Note
TS17: embryo Present There were no differences in expression in the mutant compared to control.

Specimen 7H: embryonic day 11.0; Hoxb4tm1Nrm/Hoxb4tm1Nrm (more )
Structure Level Pattern Image Note
TS18: body wall Present Regionally restricted 7H Expression was detected in the ventral body wall.

Specimen 7I: embryonic day 11.0; Hoxb2tm1Mrc/Hoxb2tm1Mrc (more )
Structure Level Pattern Image Note
TS18: body wall Trace Regionally restricted 7I Expression was dramatically reduced in the ventral body wall.
TS18: trunk mesenchyme Strong Regionally restricted 7I Expression in the trunk mesoderm was unaffected in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory