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Gene Expression Data
Assay Details
Assay
Reference: J:77820 Kameda Y, et al., Homeobox gene hoxa3 is essential for the formation of the carotid body in the mouse embryos. Dev Biol. 2002 Jul 1;247(1):197-209
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5506896
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin beta 3 (clone TUJ1, MMS-435P/801202)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1C: embryonic day 18.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 1C There is no cell stream running toward the carotid artery.

Specimen 2B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: carotid artery Present Regionally restricted 2B Expressed in the glomus cells of the carotid body.
TS24: superior cervical ganglion Present 2B

Specimen 3D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Strong 3D Expressed in the neurons.
TS26: carotid body Present 3D Expressed in the glomus cells and nerve fibers within the carotid body parenchyma.

Specimen 5B: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: common carotid artery Present Regionally restricted 5B Expressed in the carotid body rudiment as aggregations of cells in the medial wall. Dense expression in nerve fibers within the carotid body.
TS21: glossopharyngeal nerve Present 5B
TS21: superior cervical ganglion Present 5B
TS21: vagus ganglion Present 5B

Specimen 5D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: internal carotid artery Present Regionally restricted 5D Faintly expressed in the carotid body rudiment as aggregations of cells in the ventromedial wall. Dense expression in the nerve fascicules and neurons derived from the superior cervical ganglion.
TS21: glossopharyngeal nerve Present 5D
TS21: superior cervical ganglion Present 5D
TS21: vagus ganglion Present 5D

Specimen 5F: embryonic day 13.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS21: internal carotid artery Present Regionally restricted 5F Expressed in the nerve fascicules and neurons derived from the superior cervical ganglion. No carotid body rudiment was formed in the wall.
TS21: glossopharyngeal nerve Present 5F
TS21: superior cervical ganglion Present 5F
TS21: vagus ganglion Present 5F

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: common carotid artery Strong Regionally restricted Expressed in the carotid body.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory