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Gene Expression Data
Assay Details
Assay
Reference: J:66282 Packer AI, et al., Hoxa4 expression in developing mouse hair follicles and skin. Mech Dev. 2000 Dec;99(1-2):153-7
Assay type: RNA in situ
MGI Accession ID: MGI:5508654
Gene symbol: Hoxa4
Gene name: homeobox A4
Probe: Hoxa4 probe7
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa follicle Present 1A Expression was detected throughout the vibrissa follicle placode.

Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa follicle Present Regionally restricted 1B Expression was detected in the lower portion of the vibrissa follicle peg adjacent to the dermal papilla.

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vibrissa follicle Present Regionally restricted 1C Expression was detected in the innermost layer of the matrix.

Specimen 1E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present Regionally restricted 1E Expression was detected in Henle's layer of the inner root sheath. No expression was in Huxley's layer of the inner root sheath, in the outer root sheath, or in connective tissue sheath.

Specimen 1F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Present Regionally restricted 1F Expression was detected in Henle's layer of the inner root sheath. No expression was in Huxley's layer of the inner root sheath, in the outer root sheath, or in connective tissue sheath.

Specimen 1G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vibrissa follicle Present Regionally restricted 1G Expression was detected in Henle's layer of the inner root sheath. No expression was in Huxley's layer of the inner root sheath, in the outer root sheath, or in connective tissue sheath.

Specimen 1I: embryonic day 18.5; Hoxa4tm1Bhr/Hoxa4tm1Bhr (more )
Structure Level Pattern Image Note
TS26: vibrissa follicle Absent 1I No expression was seen in a section from the maxillary region.

Specimen 1K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Present 1K

Specimen 1L: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vibrissa follicle Present Regionally restricted 1L Expression was detected in the inner root sheath.

Specimen 1M: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vibrissa follicle Present Regionally restricted 1M Expression was detected in the inner root sheath.

Specimen 2A: postnatal day 2 (more )
Note: Dorsal skin.
Structure Level Pattern Image Note
TS27: hair inner root sheath Present 2A Expression was detected in inner rooth sheath precursor cells at stages 2-4.
TS27: hair root sheath matrix Present 2A Expression was detected in matrix cells at stage 4.
TS27: epidermis Present Regionally restricted 2A Expression was detected in interfollicular epidermis.

Specimen 2B: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: hair root sheath matrix Present 2B Expression was detected in matrix cells at stage 4.
TS27: dermis papillary layer Absent 2B

Specimen 2C: postnatal day 2 (more )
Note: Stage 7-8 follicle.
Structure Level Pattern Image Note
TS27: hair inner root sheath Present 2C Expression was detected at stage 7-8.
TS27: hair outer root sheath Present 2C Expression was detected at stage 7-8.
TS27: epidermis Present Regionally restricted 2C Expression was detected in interfollicular epidermis.

Specimen 2D: postnatal day 2; Hoxa4tm1Bhr/Hoxa4tm1Bhr (more )
Structure Level Pattern Image Note
TS27: hair follicle Absent 2D

Specimen 2E: postnatal day 5.5 (more )
Note: Mid-anagen follicles.
Structure Level Pattern Image Note
TS28: hair follicle Absent 2E

Specimen 2F: postnatal day 5.5 (more )
Note: Mid-anagen follicles.
Structure Level Pattern Image Note
TS28: hair follicle Absent 2F

Specimen not shown: postnatal day 9 (more )
Note: Late anagen follicles.
Structure Level Pattern Image Note
TS28: hair follicle Absent

Specimen 2G: postnatal day 17 (more )
Note: Catagen follicle.
Structure Level Pattern Image Note
TS28: hair follicle Absent 2G

Specimen 2H: postnatal week 8 (more )
Note: Telogen follicle.
Structure Level Pattern Image Note
TS28: hair follicle Absent 2H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory