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Gene Expression Data
Assay Details
Assay
Reference: J:165469 Sadakata T, et al., Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain. J Comp Neurol. 2006 Apr 20;495(6):735-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5509038
Gene symbol: Cadps2
Gene name: Ca2+-dependent activator protein for secretion 2
Antibody: anti-a1803/CAPS2
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: olfactory cortex Moderate Regionally restricted 1A Expression is in the anterior olfactory nucleus.
TS24: telencephalon Weak 1A

Specimen 1C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: thalamus Present Regionally restricted 1C Expression is in the lateral posterior thalamic nucleus.

Specimen 1E: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: forebrain Present Regionally restricted 1E Expression is in the subcommissural organ.
TS24: epithalamus Present Regionally restricted 1E Expression is in the lateral habenular nucleus.

Specimen 1G: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Very strong Regionally restricted 1G Expression is in the dorsomedial and ventromedial hypothalamic nuclei.
TS24: pons Moderate Regionally restricted 1G Expression is in the pontine nucleus.

Specimen 1I: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: midbrain Present Regionally restricted 1I Expression is in the mammillothalamic tract and in the ventral tegmental area.

Specimen 1K: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cerebellum Strong Regionally restricted 1K Strongest staining in cells of the external germinal layer and in cells scattered underneath it.

Specimen 1M: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Present 1M
TS24: spinal cord Present 1M

Specimen 1O: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: dorsal root ganglion Present 1O

Specimen 2B: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 2B

Specimen 2C: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer Strong Regionally restricted 2C Expression is in the somata and neurites of a subset of granule cells scattered around the mitral cell layer.

Specimen 2D: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present Regionally restricted 2D Expression is in a subpopulation of anterior olfactory nuclei.

Specimen 2E: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: corpus striatum Present Regionally restricted 2E Expression is in striatal neurons dispersed in the cortico-striatal fiber system.

Specimen 2F,H: postnatal day 8 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: cortical layer V Present Regionally restricted 2F , 2H
TS28: cerebral cortex Present Single cells 2H , 2F Expression is in cortical interneurons.

Specimen 2I: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Strong 2I In the CA1 region.
TS28: hippocampus molecular layer Strong Single cells 2I In the CA1 region.
TS28: hippocampus stratum lacunosum Strong Single cells 2I In the CA1 region.

Specimen 2J: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: hippocampus stratum lucidum Strong Regionally restricted 2J In the CA3 region.
TS28: subiculum Strong Regionally restricted 2J Expression is in subicular cells and fibers.
TS28: dentate gyrus hilus Present 2J
TS28: dentate gyrus layer Present Single cells 2J Expression is in a few cells adjoining the dentate granule layer.

Specimen 2K: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: lateral habenular nucleus Very strong 2K
TS28: medial habenular nucleus Very strong 2K

Specimen 2L,N: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: anterior ventral thalamic nucleus Very strong 2N , 2L

Specimen 3A: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 3A

Specimen 3B: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: substantia nigra Present 3B

Specimen 3C: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: red nucleus Present 3C

Specimen 3D: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: pontine nucleus Absent 3D

Specimen 3E: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Strong 3E
TS28: cerebellum internal granule cell layer Moderate 3E

Specimen 3F: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: deep cerebellar nucleus Absent 3F Absent in medial cerebellar nucleus, interposed anterior cerebellar nucleus, and the interposed posterior cerebellar nucleus.

Specimen 3G: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 3G Expression is in the tenia choroidea.

Specimen 3H: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: medulla oblongata Present Regionally restricted 3H Expression is in a subset of vestibular neurons.

Specimen 3I: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: inferior olivary nucleus Absent 3I

Specimen 3J: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: cuneate nucleus Absent 3J

Specimen 3K: postnatal day 8 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Present Regionally restricted 3K Expression is in lamina II neurons.

Specimen 3L: postnatal day 8 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: spinal cord ventral horn Present Regionally restricted 3L Expression is in interneurons.

Specimen 4E,G: postnatal day 8 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: hippocampus molecular layer Very strong Regionally restricted 4G , 4E In the CA1 subfield.
TS28: hippocampus pyramidal cell layer Very strong Regionally restricted 4G , 4E In the CA1 subfield.
TS28: hippocampus stratum lacunosum Very strong Regionally restricted 4G , 4E In the CA1 subfield.
TS28: hippocampus stratum oriens Very strong Regionally restricted 4G , 4E In the CA1 subfield.
TS28: hippocampus stratum radiatum Very strong Regionally restricted 4G , 4E In the CA1 subfield.
TS28: hippocampus stratum lucidum Very strong Regionally restricted 4E , 4G In the CA3 subfield.
TS28: dentate gyrus hilus Very strong 4G , 4E
TS28: hippocampus Very strong 4E , 4G Expression is in the alveus and in small cell populations that are scattered over the hippocampus.
TS28: dentate gyrus molecular layer Present 4E , 4G Expression is in the inner molecular layer.

Specimen 4H,J: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: hippocampus molecular layer Very strong Regionally restricted 4H , 4J In the CA1 subfield.
TS28: hippocampus pyramidal cell layer Very strong Regionally restricted 4H , 4J In the CA1 subfield.
TS28: hippocampus stratum lacunosum Very strong Regionally restricted 4H , 4J In the CA1 subfield.
TS28: hippocampus stratum oriens Very strong Regionally restricted 4H , 4J In the CA1 subfield.
TS28: hippocampus stratum radiatum Very strong Regionally restricted 4H , 4J In the CA1 subfield.
TS28: hippocampus stratum lucidum Very strong Regionally restricted 4H , 4J In the CA3 subfield.
TS28: dentate gyrus Very strong 4J , 4H
TS28: hippocampus Very strong Regionally restricted 4J , 4H Expression is in the alveus and in small cell populations that are scattered over the hippocampus.
TS28: dentate gyrus molecular layer Present Regionally restricted 4H , 4J Expression is in the inner molecular layer.

Specimen 4K,M: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: hippocampus molecular layer Present Regionally restricted 4K , 4M Expressing cells are near the interface region between these layers of the CA1 region.
TS28: hippocampus stratum lacunosum Present Regionally restricted 4K , 4M Expressing cells are near the interface region between these layers of the CA1 region.
TS28: hippocampus stratum radiatum Present Regionally restricted 4K , 4M Expressing cells are near the interface region between these layers of the CA1 region.

Specimen 4N,P: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Cadps (assay MGI:5509066).
Structure Level Pattern Image Note
TS28: dentate gyrus Present Regionally restricted 4P , 4N Expression is between the granule cells and the polymorphic layers.

Specimen 5A,D: postnatal day 21 (more )
Note: Triple labeled: green - Cadps2; blue - Cadps (assay MGI:5509066); red - Th (assay MGI:5509067).
Structure Level Pattern Image Note
TS28: interpeduncular nucleus Present 5D , 5A
TS28: substantia nigra Present 5D , 5A
TS28: ventral tegmental area Present 5D , 5A

Specimen 7A: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp1 (assay MGI:5509173) and Vamp2 (assay MGI:5509176).
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 7A

Specimen 7B: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp3 (assay MGI:5509177).
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 7B

Specimen 7C: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp4 (assay MGI:5509178).
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 7C

Specimen 7G: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Snap25 (assay MGI:5509179).
Structure Level Pattern Image Note
TS28: ventral tegmental area Present 7G

Specimen 8A: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp1 (assay MGI:5509173) and Vamp2 (assay MGI:5509176).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present 8A

Specimen 8B: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp3 (assay MGI:5509177).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present 8B

Specimen 8C: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Vamp4 (assay MGI:5509178).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present 8C

Specimen 8G: postnatal day 21 (more )
Note: Double labeled: green - Cadps2; red - Snap25 (assay MGI:5509179).
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present 8G

Specimen Table 1 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: hypothalamus Strong Regionally restricted Expression is in the dorsomedial hypothalamic and ventromedial hypothalamic nuclei absent in the arcuate hypothalamic nucleus.
TS24: cerebellum Strong Regionally restricted Expression is in the external granular layer.
TS24: brain Strong Regionally restricted Expression is in the subcommissural organ.
TS24: olfactory cortex Moderate Regionally restricted Expression is in the anterior olfactory nucleus.
TS24: midbrain Moderate Regionally restricted Expression is in the ventral tegmental area and substantia nigra.
TS24: pons Moderate Regionally restricted Expression is in the pontine nucleus.
TS24: dorsal root ganglion Moderate
TS24: spinal cord Moderate
TS24: adenohypophysis Weak
TS24: thalamus Weak Regionally restricted Expression is in the thalamus, mammillothalamic nucleus, and the lateraldorsal and lateroposterior thalamic nuclei.
TS24: choroid plexus Absent
TS24: telencephalon septum Absent

Specimen Table 1 P21: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Strong
TS28: dentate gyrus hilus Strong
TS28: subiculum Strong
TS28: substantia nigra Strong
TS28: ventral tegmental area Strong
TS28: hippocampus stratum radiatum Strong Regionally restricted CA1 region, absent in CA3 region.
TS28: anterior olfactory nucleus Moderate
TS28: anterior ventral thalamic nucleus Moderate
TS28: choroid plexus Moderate
TS28: cortical layer V Moderate
TS28: interpeduncular nucleus Moderate
TS28: lateral habenular nucleus Moderate
TS28: main olfactory bulb mitral cell layer Moderate
TS28: medial habenular nucleus Moderate
TS28: red nucleus Moderate
TS28: spinal cord Moderate
TS28: vestibular nucleus Moderate
TS28: dentate gyrus molecular layer Moderate Regionally restricted The inner layer.
TS28: hippocampus Moderate Regionally restricted The inner layer.
TS28: hippocampus CA1 Moderate Regionally restricted Expression is in the alveus.
TS28: hippocampus pyramidal cell layer Moderate Regionally restricted In the CA1 region, absent in CA3 region.
TS28: hippocampus stratum lucidum Moderate Regionally restricted In the CA1 and CA3 region.
TS28: corpus striatum Weak
TS28: cortical layer I Weak
TS28: cortical layer IV Weak
TS28: cortical layer VI Weak
TS28: dorsal root ganglion Weak
TS28: hippocampus molecular layer Weak Regionally restricted Expression is in the CA1 region.
TS28: hippocampus stratum lacunosum Weak Regionally restricted Expression is in the CA1 region.
TS28: hippocampus stratum oriens Weak Regionally restricted Expression is in the CA1 region.
TS28: cerebellum internal granule cell layer Trace
TS28: anterior dorsal thalamic nucleus Absent
TS28: cerebellum Purkinje cell layer Absent
TS28: cuneate nucleus Absent
TS28: deep cerebellar nucleus Absent
TS28: dentate gyrus granule cell layer Absent
TS28: inferior olivary nucleus Absent
TS28: main olfactory bulb external plexiform layer Absent
TS28: main olfactory bulb glomerular layer Absent
TS28: main olfactory bulb granule cell layer Absent
TS28: main olfactory bulb internal plexiform layer Absent
TS28: pontine nucleus Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory