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Gene Expression Data
Assay Details
Assay
Reference: J:209852 Prandi S, et al., A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131. PLoS One. 2013;8(12):e82820
Assay type: Recombinase reporter
MGI Accession ID: MGI:5572957
Gene symbol: Tas2r131
Gene name: taste receptor, type 2, member 131
Reporter: RFP
Direct Detection
Results
Specimen 3A: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present 3A GLP-1 left , 3A Cga left RFP-labeled cells in the colon do not show co-localization with enteroendocrine cell markers GLP-1 or chromogranin A.
Specimen 3B: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present 3B CK18 left , 3B villin left RFP-labeled cells in the colon do not show co-localization with markers for brush cells (cy6okeratin 18) or brush border membranes (villin).
Specimen 3C: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present 3C mucin-2 left RRFP-labeled cells in the colon do not show co-localization with the marker for goblet cells (mucin-2).
Specimen 3D: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present 3D a-gustducin left , 3D PLC beta2 left RFP-labeled cells in the colon do not show co-localization with taste cell markers (alpha-gustducin or PLCbeta2).
Specimen Data not shown: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted RFP-labeled cells are observed in the luminal and crypt mucosa.
TS28: colon mucosa Present
TS28: crypt of lieberkuhn Present Non-Uniform Some crypts are completely labeled by RFP.
Specimen S2A: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present S2A RFP labeling is observed in a cell with goblet cell located at the mouth of a crypt in the colon.
TS28: crypt of lieberkuhn Present Regionally restricted S2A
Specimen S2B: postnatal; Gt(ROSA)26Sortm1Hjf/Gt(ROSA)26Sor+, Tas2r131tm2.1(cre)Uboe/Tas2r131+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: colon Present S2B RFP labeling is observed in a cell with colonocyte morphology.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory