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Gene Expression Data
Assay Details
Assay
Reference: J:187968 Okano J, et al., The regulation of endogenous retinoic acid level through CYP26B1 is required for elevation of palatal shelves. Dev Dyn. 2012 Nov;241(11):1744-56
Assay type: RNA in situ
MGI Accession ID: MGI:5603193
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 probe25
Probe preparation: Antisense
Results
Specimen 8A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: palatal shelf mesenchyme Weak 8A
TS19: tongue Weak 8A
TS19: mandible primordium Present 8A
Specimen 8B: embryonic day 11.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Structure Level Pattern Image Note
TS19: palatal shelf mesenchyme Absent 8B
TS19: mandible primordium Present 8B Reduced expression compared with wild-type.
TS19: tongue Present 8B Reduced expression compared with wild-type.
Specimen 8C: embryonic day 11.75 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present 8C
TS20: palatal shelf mesenchyme Present 8C
TS20: tongue Present 8C
Specimen 8D: embryonic day 11.75; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present 8D Decreased expression compared with the wild-type.
TS20: tongue Present 8D Decreased expression compared with the wild-type.
TS20: palatal shelf mesenchyme Absent 8D
Specimen 8E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Present Regionally restricted 8E Expressed in the bend region as well as in the mesenchyme of middle palatal shelves.
TS20: oral region gland Present Regionally restricted 8E Expressed in the submandibular gland primordia.
TS20: mandible primordium Present 8E
TS20: tongue Present 8E
Specimen 8F: embryonic day 12.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Structure Level Pattern Image Note
TS20: palatal shelf mesenchyme Weak Regionally restricted 8F Expressed in the ventrolateral mesenchyme but was absent in the bend region.
TS20: oral region gland Present Regionally restricted 8F Expressed in the submandibular gland primordia, similar to the wild-type.
TS20: mandible primordium Present 8F
TS20: tongue Present 8F
Specimen 8G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Regionally restricted 8G Expressed in the bend region as well as in the mesenchyme of middle palatal shelves.
TS21: mandible Present 8G
TS21: submandibular gland primordium Present 8G
TS21: tongue Present 8G
Specimen 8H: embryonic day 13.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Weak Regionally restricted 8H Expressed in the ventrolateral mesenchyme but was absent in the bend region.
TS21: mandible Present 8H Similar to the wild-type.
TS21: submandibular gland primordium Present 8H Similar to the wild-type.
TS21: tongue Present 8H Similar to the wild-type.
Specimen 9F/H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 9F , 9H
Specimen 9G/I: embryonic day 13.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 9G , 9I Maintained expression in the bend region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory