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Gene Expression Data
Assay Details
Assay
Reference: J:96466 Singh MK, et al., The T-box transcription factor Tbx15 is required for skeletal development. Mech Dev. 2005 Feb;122(2):131-44
Assay type: RNA in situ
MGI Accession ID: MGI:5605359
Gene symbol: Tbx15
Gene name: T-box 15
Probe: Tbx15 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud Present 1A

Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 1B , 1B inset Expression is along the proximo-distal extension in the central region and is absent in the anterior and posterior edges.
TS17: head Present Regionally restricted 1B There is an expression domain above the eye.
TS17: hindlimb bud Present 1B

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1C Expression is along the proximo-distal extension in the central region and is absent in the anterior and posterior edges.
TS19: head Present Regionally restricted 1C There is an expression domain above the eye.
TS19: hindlimb bud Present 1C

Specimen 1D: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forelimb Present Regionally restricted 1D Expression is along the proximo-distal extension in the central region and is absent in the anterior and posterior edges.
TS20: hindlimb Present 1D

Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head mesenchyme Present Regionally restricted 1E Expression is in the unsegmented cranial mesenchyme.

Specimen 1F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Strong Regionally restricted 1F Expression is highest in the central core of the forelimb bud.

Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Present Regionally restricted 1G Expression is in the unsegmented cranial mesenchyme.

Specimen 1H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present Regionally restricted 1H Expression is weak in the condensing cells and strong in the surrounding mesenchyme.

Specimen 1I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 1I , 1K Expression is weak in the condensing cells and strong in the surrounding mesenchyme.
TS20: chondrocranium Present Regionally restricted 1I , 1J Expression is downregulated upon condensation of mesenchymal cells into the primordia of the skeletal elements of the basioccipital bone.
TS20: vertebral cartilage condensation Present Regionally restricted 1I Expression is in mesenchymal cells surrounding the condensations of the vertebral bodies.

Specimen 1L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb mesenchyme Present Regionally restricted 1O , 1L Expression is weak in the condensing cells and strong in the surrounding mesenchyme.
TS22: hindlimb Present Regionally restricted 1O , 1L Expression is high in the developing joints, the articular mesenchyme, and the perichondrium.
TS22: basioccipital cartilage condensation Present Regionally restricted 1M , 1L Expression is maintained in mesenchymal cells surrounding the condensations, whereas resting and proliferating chondrocytes show lower expression.
TS22: vertebral cartilage condensation Present Regionally restricted 1L Expression is in mesenchymal cells surrounding the condensations of the vertebral bodies.
TS22: skeletal muscle Present 1L

Specimen 1P: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hand mesenchyme Strong Regionally restricted 1P Expression is high in the developing joints, the articular mesenchyme, and the perichondrium.
TS23: forelimb digit 2 Present 1P
TS23: forelimb digit 3 Present 1P
TS23: forelimb digit 4 Present 1P
TS23: forelimb digit 1 Absent 1P
TS23: forelimb digit 5 Absent 1P

Specimen 1Q: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Present Regionally restricted 1Q Expression is in the resting chondrocytes of the proximal region of the humerus.
TS23: skeletal muscle Present 1Q

Specimen 1R: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 1R Expression is in the resting chondrocytes of the proximal region of the humerus.
TS24: skeletal muscle Present 1R

Specimen 1S: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: skeletal muscle Present 1S
TS26: humerus Absent 1S


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory