Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:221197
Yao W, et al., Cell type-restricted expression of erythrocyte tropomodulin Isoform41 in exon 1 knockout/LacZ knock-in heterozygous mice. Gene Expr Patterns. 2015 Jan;17(1):45-55
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Assay type:
|
In situ reporter (knock in)
|
MGI Accession ID:
|
MGI:5696817
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Gene symbol:
|
Tmod1
|
Gene name:
|
tropomodulin 1
|
Reporter:
|
lacZ
|
|
Direct Detection
|
|
Results
|
Specimen
2A:
embryonic day 10.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
2A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: blood |
Strong |
Regionally restricted |
2A
|
High level of expression in large primitive erythroblasts circulating through the dorsal aorta.
|
TS17: embryo |
Present |
Single cells |
2A
|
Authors report expression outside of blood vessels in the embryo proper. It was not clear whether these were erythroblasts or other cells migrating in the tissues.
|
Specimen
2B:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
2B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: blood |
Weak |
Regionally restricted |
2B
|
Weak perinuclear expression in erythroblasts circulating to the heart.
|
Specimen
2C:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
2C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: liver |
Present |
Regionally restricted |
2C
|
Expression in definitive erythrocytes in the liver.
|
Specimen
2D:
embryonic day 14.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
2D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: blood |
Present |
Regionally restricted |
2D
|
Expression in only a few definitive erythrocytes in the heart.
|
Specimen
3A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Patchy |
3A
|
Patchy expression in erythroid cells of different sizes, with expression more prevalent as cell size decreased.
|
Specimen
3B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: spleen |
Strong |
Regionally restricted |
3B
|
Expression only in mature erythrocytes.
|
Specimen
3C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: blood |
Present |
Regionally restricted |
3C
|
Expression in 10% of erythrocytes in peripheral blood.
|
Specimen
4A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: renal cortex |
Present |
Regionally restricted |
4A
|
Expression restricted to tubular structures in the superficial region of renal cortex.
|
Specimen
4B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
4C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
4D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cortical renal tubule |
Present |
Regionally restricted |
4D
|
Expression in tubular structures of the renal cortex that are short in length, likely to be distal convoluted tubules, connecting tubules and/or initial connecting tubules.
|
TS28: glomerular tuft |
Absent |
|
4D
|
|
Specimen
5A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
5B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
5C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lung |
Present |
Regionally restricted |
5C
|
Expression in smooth muscle cells.
|
Specimen
5D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: skin muscle |
Present |
|
5D
|
Expression in smooth muscle cells.
|
Specimen
not shown E8.0:
embryonic day 8.0; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
not shown E8.0:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 8.0
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Specimen
not shown E9.5:
embryonic day 9.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
not shown E9.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Specimen
6A:
embryonic day 10.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
6A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: somite |
Weak |
Patchy |
6A
|
Patchy low level expression in rostral somites.
|
Specimen
6B:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
6B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: myotome |
Present |
|
6B
|
Higher expression in elongating myotome cells of rostral somites.
|
Specimen
6C:
embryonic day 14.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
6C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: somite |
Present |
|
6C
|
Increased expression in rostral somites.
|
Specimen
6D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7A E10.5:
embryonic day 10.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
7A E10.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
7A E11.5:
embryonic day 11.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
7A E11.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
7A E12.5:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
7A E12.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
7A E13.5:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
7A E13.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
7B.C:
embryonic day 12.5; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
7B.C:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section from whole mount
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: lens vesicle |
Present |
Regionally restricted |
7C
,
7B
|
Expression in lens fibers.
|
Specimen
7D:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lens fiber |
Present |
Regionally restricted |
7D
|
Expression only in cortical fiber cells, not is cells located toward the center of the lens.
|
Specimen
8A:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal day 3
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: retina |
Weak |
Scattered |
8A
|
More expression in cells close to the pigment layer.
|
Specimen
not shown P7:
postnatal day 7; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
not shown P7:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal day 7
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: retina |
Present |
Regionally restricted |
|
Expression confined to a single layer of cells.
|
Specimen
not shown P15:
postnatal day 15; Tmod1tm1Sung/Tmod1 +
(more )
Specimen
not shown P15:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal day 15
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: retina |
Present |
Regionally restricted |
|
Expression confined to a single layer of cells.
|
Specimen
8B:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ
|
Mutant Allele(s):
|
Tmod1tm1Sung/Tmod1+
|
Age:
|
postnatal adult
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: retina inner nuclear layer |
Present |
Regionally restricted |
8B
|
Authors report expression in cells oriented horizontally at the outer plexiform layer, with their cell bodies positioned in the inner nuclear layer.
|
TS28: retina outer plexiform layer |
Present |
Regionally restricted |
8B
|
Authors report expression in cells oriented horizontally at the outer plexiform layer, with their cell bodies positioned in the inner nuclear layer.
|
|