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Gene Expression Data
Assay Details
Assay
Reference: J:211182 Deng M, et al., Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons. Gene Expr Patterns. 2014 May;15(1):31-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5697837
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3A/C: embryonic day 10.5 (more )
Note: Double labeled: red - Isl1; green - Neurod1 (assay MGI:5697838).
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 3C , 3A Co-expressed with Neurod1 at the base of the otic epithelium, but not in the Neurod1-positive cells located more apically within the otic epithelium.
TS17: acoustic ganglion Present Regionally restricted 3C , 3A Co-expressed with Neurod1 in the delaminated cochleovestibular ganglion cells.
Specimen 3D/F: embryonic day 10.5; Neurod1tm1Mjts/Neurod1tm1Mjts (more )
Note: Double labeled: red - Isl1; green - Mki67 (assay MGI:5697840).
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 3D , 3F Expressed in proliferating cells as well as in post-mitotic cells in the cochleovestibular ganglion.
TS17: facial ganglion Present 3D , 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
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