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Gene Expression Data
Assay Details
Assay
Reference: J:226614 Costello I, et al., Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev. 2015 Oct 15;29(20):2108-22
Assay type: RNA in situ
MGI Accession ID: MGI:5701370
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Probe: Lhx1 cDNA10
Probe preparation: Antisense RNA
Results
Specimen S1D: embryonic day 7.5; Lhx1tm1.1(icre)Rob/Lhx1+ (more )
Structure Level Pattern Image Note
TS11: conceptus Present S1D Lhx1
Specimen 1F Control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 1F Control Expression is seen at the midline.
TS11: anterior visceral endoderm Present 1F Control
Specimen 1F Mutant: embryonic day 7.5; Eomestm1Rob/Eomestm1.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo mesoderm Absent 1F Eomes delta Epi Expression is eliminated in the epiblast in the mutant.
TS11: anterior visceral endoderm Present 1F Eomes delta Epi This tissue is genetically wild type in these animals.
Specimen 1G Control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 1G Control Expression is seen at the midline.
TS11: anterior visceral endoderm Present 1G Control
Specimen 1G Mutant: embryonic day 7.5; Smad4tm1Rob/Smad4tm1.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: embryo mesoderm Absent 1G Smad4 delta Epi Expression is eliminated in the epiblast in the mutant.
TS11: anterior visceral endoderm Present 1G Smad4 delta Epi This tissue is genetically wild type in these animals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory