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Gene Expression Data
Assay Details
Assay
Reference: J:226614 Costello I, et al., Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development. Genes Dev. 2015 Oct 15;29(20):2108-22
Assay type: RNA in situ
MGI Accession ID: MGI:5701401
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: pOtd9
Probe preparation: Antisense RNA
Results
Specimen S2H Control: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Present S2H Control
TS13: future prosencephalon Present S2H Control
Specimen S2H Mutant: embryonic day 8.5; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: embryo Absent S2H Lhx1 delta Epi These embryos lack head structures anterior of the otic vesicle.
Specimen S4A Control: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: conceptus Present Regionally restricted S4A Control
Specimen S4A Mutant: embryonic day 7.5; Lhx1tm1Bhr/Lhx1tm2.1Rob, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: conceptus Present Regionally restricted S4A Lhx1 delta Epi Expression levels are reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory