Gene Expression Data
Assay Details
Assay
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Reference:
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J:40260
Geng L, et al., Distribution and developmentally regulated expression of murine polycystin. Am J Physiol. 1997 Apr;272(4 Pt 2):F451-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5707481
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Gene symbol:
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Pkd1
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Gene name:
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polycystin 1, transient receptor potential channel interacting
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Antibody:
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mpkcr-Ab
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
E10.5 not shown:
embryonic day 10.5
(more )
Specimen
E10.5 not shown:
(close )
Genetic Background:
|
Not Specified
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Age:
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embryonic day 10.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS17: metanephric mesenchyme |
Ambiguous |
|
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Authors report expression above background level but no clearly stained structures in kidneys prior to E13.5
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Specimen
E13.5 not shown:
embryonic day 13.5
(more )
Specimen
E13.5 not shown:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7A:
embryonic day 15.5
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7B:
embryonic day 15.5
(more )
Specimen
7B:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS23: collecting duct |
Present |
Regionally restricted |
7B
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Expression in the ureteric bud and collecting ducts.
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TS23: comma-shaped body |
Absent |
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7B
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No expression in in mesenchyme-derived structures: at early stages condensates, comma- or S-shaped bodies.
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TS23: s-shaped body |
Absent |
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7B
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No expression in in mesenchyme-derived structures: at early stages condensates, comma- or S-shaped bodies.
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Specimen
7C:
embryonic day 15.5
(more )
Specimen
7C:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
|
Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7D:
embryonic day 15.5
(more )
Specimen
7D:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 15.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7E:
embryonic day 15.5
(more )
Specimen
7E:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 15.5
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS23: collecting duct |
Present |
Regionally restricted |
7E
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Expression more intense near the apical membrane.
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Specimen
7F:
embryonic day 18.0
(more )
Specimen
7F:
(close )
Genetic Background:
|
Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: inner medullary collecting duct |
Strong |
Regionally restricted |
7F
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High levels of expression in collecting ducts, in both papillary ducts in the medulla, and in straight collecting ducts of the periphery.
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TS26: outer medullary collecting duct |
Strong |
Regionally restricted |
7F
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High levels of expression in collecting ducts, in both papillary ducts in the medulla, and in straight collecting ducts of the periphery.
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TS26: inner renal medulla |
Present |
Regionally restricted |
7F
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Expression in renal papillae, slightly weaker than in the collecting ducts in the outer medulla.
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TS26: ureter |
Strong |
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7F
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TS26: renal vasculature |
Absent |
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7F
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No expression in endothelial or smooth muscle cells in renal vessels.
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TS26: metanephros |
Present |
Regionally restricted |
7F
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Spatial distribution of expression is maintained with no obvious decrease in the level of expression.
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Specimen
7G:
postnatal newborn
(more )
Specimen
7G:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: collecting duct |
Present |
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7G
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TS27: inner renal medulla |
Present |
Regionally restricted |
7G
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Expression in renal papillae, slightly weaker than in the collecting ducts in the outer medulla.
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TS27: metanephros |
Present |
Regionally restricted |
7G
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Spatial distribution of expression is maintained with no obvious decrease in the level of expression.
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Specimen
7H:
postnatal week 1
(more )
Specimen
7H:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal week 1
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Sex:
|
Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
7I:
postnatal week 1
(more )
Specimen
7I:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal week 1
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: collecting duct |
Present |
|
7I
|
|
TS28: inner renal medulla |
Strong |
Regionally restricted |
7I
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High levels of expression in renal papillae.
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TS28: metanephros |
Present |
Regionally restricted |
7I
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Spatial distribution of expression is maintained with no obvious decrease in the level of expression.
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Specimen
P day 21 not shown:
postnatal day 21
(more )
Specimen
P day 21 not shown:
(close )
Genetic Background:
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Not Specified
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Age:
|
postnatal day 21
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: collecting duct |
Trace |
|
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Expression in collecting system decreased to a very low level, just above background levels.
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Specimen
7J:
postnatal adult
(more )
Specimen
7J:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: collecting duct |
Trace |
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7J
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Expression in collecting ducts just above background levels.
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Specimen
8A:
postnatal day 3
(more )
Specimen
8A:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 3
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS27: hepatic duct |
Strong |
|
8A
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High expression in epithelial cells of hepatic bile ducts.
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TS27: liver |
Weak |
Regionally restricted |
8A
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Weak expression in hepatocytes and acinar cells.
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TS27: portal vein |
Absent |
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8A
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Specimen
8B:
postnatal day 3
(more )
Specimen
8B:
(close )
Genetic Background:
|
Not Specified
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Age:
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postnatal day 3
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Specimen
8C:
postnatal day 3
(more )
Specimen
8C:
(close )
Genetic Background:
|
Not Specified
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Age:
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postnatal day 3
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Sex:
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Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Specimen
8D:
postnatal day 3
(more )
Specimen
8D:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal day 3
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Sex:
|
Not Specified
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Type:
|
section
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Embedding:
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Cryosection
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Specimen
8E:
postnatal day 3
(more )
Specimen
8E:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal day 3
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
8F:
postnatal day 3
(more )
Specimen
8F:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal day 3
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Sex:
|
Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
spleen not shown:
postnatal day 3
(more )
Specimen
spleen not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 3
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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