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Gene Expression Data
Assay Details
Assay
Reference: J:203004 Karunakaran DK, et al., The expression analysis of Sfrs10 and Celf4 during mouse retinal development. Gene Expr Patterns. 2013 Dec;13(8):425-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5749767
Gene symbol: Celf4
Gene name: CUGBP, Elav-like family member 4
Antibody: BRUNOL4 antibody (G-19)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 8A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted 8A Lower expression at E12, restricted to differentiating retinal neurons.
Specimen 8B: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 8B Expression in the nuclei, and also in the cytoplasm, enriched asymmetrically toward the newly forming projections. Expression in differentiating amacrine cells at bottom of outer neuroblastic layers abutting the inner plexiform layer.
Specimen 8C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 8C Expression in the nuclei, and also in the cytoplasm, enriched asymmetrically toward the newly forming projections. Expression in differentiating amacrine cells at bottom of outer neuroblastic layers abutting the inner plexiform layer.
Specimen 8D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: retina Present Regionally restricted 8D Expression in the nuclei, and also in the cytoplasm, enriched asymmetrically toward the newly forming projections.
TS26: retina outer nuclear layer Present Regionally restricted 8D Expression also observed in differentiating amacrine cells localized at bottom of outer neuroblastic layers abutting the newly formed inner plexiform layer.
Specimen 8E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 8E
TS27: retina inner plexiform layer Present 8E
TS27: retina outer plexiform layer Present 8E
Specimen 8F: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Regionally restricted 8F
TS28: retina inner plexiform layer Present Regionally restricted 8F
TS28: retina outer plexiform layer Present Regionally restricted 8F
Specimen 8F inset: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Regionally restricted 8F inset Enriched expression in the initial segment of the newly forming axons of the ganglion cells.
Specimen 8G: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8G Expression predominantly in cytoplasm of bipolar and amacrine cells. Also detected in nucleus of ganglion cells.
Specimen 8H: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8H Expression predominantly in cytoplasm of bipolar and amacrine cells. Also detected in nucleus of ganglion cells.
Specimen 8I: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8I Expression in bipolar cells and ganglion cells.
Specimen 9A/C: postnatal day 14 (more )
Note: Double labeled: red - Celf4; blue - Isl1 (assay MGI:5749769).
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 9A , 9C Expression in bipolar cells and ganglion cells.
Specimen 9D/F: postnatal day 14 (more )
Note: Triple labeled: red - Celf4; green - Glul (assay MGI:5749771); blue - DAPI.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 9F , 9D No expression in Mueller glia.
Specimen 10A: postnatal day 14 (more )
Note: Double labeled: red - Celf4; green - Prkca (assay MGI:5749772).
Structure Level Pattern Image Note
TS28: retina inner plexiform layer Present Regionally restricted 10A Celf4 , 10A merge Expression in synaptic boutons in the inner plexiform layer.
TS28: retina outer plexiform layer Present Regionally restricted 10A Celf4 , 10A merge Expression in synapses in the newly forming outer plexiform layer.
Specimen 11A/C: postnatal adult (more )
Note: Triple labeled: red - Celf4; green - Prkca (assay MGI:5749772); blue - DAPI.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 11A , 11C
Specimen 11D: postnatal adult (more )
Note: Triple labeled: red - Celf4; green - Prkca (assay MGI:5749772); blue - DAPI.
Structure Level Pattern Image Note
TS28: retina outer plexiform layer Present 11D
Specimen 11E: postnatal adult (more )
Note: Triple labeled: red - Celf4; green - Prkca (assay MGI:5749772); blue - DAPI.
Structure Level Pattern Image Note
TS28: retina inner plexiform layer Present Regionally restricted 11E Expression in synaptic boutons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory