About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:11609 Pelton RW, et al., In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development. 1990 Oct;110(2):609-20
Assay type: RNA in situ
MGI Accession ID: MGI:5758942
Gene symbol: Tgfb1
Gene name: transforming growth factor, beta 1
Probe: Tgfb1 probe4
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probes were reduced to an average size of 100-150 nucleotides by limited alkaline hydrolysis.
Results
Specimen 3A/D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindlimb skeleton Present Regionally restricted 3A/D Expression is in the perichondrium surrounding the mature cartilage.
Specimen 4B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: maxilla Present Regionally restricted 4B Expression is in osetoblasts.
Specimen 5A/D: embryonic day 13.5 (more )
Note: Bud stage tooth.
Structure Level Pattern Image Note
TS21: tooth mesenchyme Present Regionally restricted 5A/D Expression is in the condensed neural crest mesenchyme.
TS21: tooth epithelium Present Regionally restricted 5A/D Expression is in the ameloblast primordium.
Specimen 5G/J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental papilla Very strong Regionally restricted 5G/J Expression is in the mesenchymal primordium of the pulp and is absent in odontoblasts.
TS24: enamel organ Absent 5G/J
Specimen 6G/H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: liver Present Single cells 6G/H Expression is in megakaryocytes, absent in the capsule.
TS19: liver parenchyma Absent 6G/H
Specimen 8A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vomeronasal organ mesenchyme Present Punctate 8A/B Expression is in the mesenchyme directly adjacent to the neuroepithelium.
TS21: vomeronasal organ epithelium Absent 8A/B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory