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Gene Expression Data
Assay Details
Assay
Reference: J:97216 Weninger WJ, et al., Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development. Development. 2005 Mar;132(6):1337-48
Assay type: RNA in situ
MGI Accession ID: MGI:5789009
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2 probe19
Probe preparation: Antisense RNA
Results
Specimen 3J: embryonic day 9.0 (more )
Note: 12-14 somite stage embryo.
Structure Level Pattern Image Note
TS14: embryo mesoderm Present Regionally restricted 3J Expression is in the left lateral mesoderm.
TS14: sinus venosus left horn Present 3J
Specimen 3K: embryonic day 9.0; Cited2tm1Jpmb/Cited2+ (more )
Note: 12-14 somite stage embryo.
Structure Level Pattern Image Note
TS14: embryo mesoderm Present Regionally restricted 3K Expression is in the left lateral mesoderm.
TS14: sinus venosus left horn Present 3K
Specimen 3L: embryonic day 9.0; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 12-14 somite stage embryo.
Structure Level Pattern Image Note
TS14: embryo mesoderm Present Regionally restricted 3L Expression is absent in the left lateral mesoderm in 4 out 12 embryos.
Specimen 3M: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: right ventricle cardiac muscle Present Regionally restricted 3M Expression is in the ventral myocardium.
TS21: left atrium Present 3M
TS21: heart Present Regionally restricted 3M Expression is in the ventral veins.
Specimen 3N: embryonic day 13.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 3N This mutant lacks a laterality defect and expression is as in wild-type.
TS21: left atrium Present Regionally restricted 3N This mutant lacks a laterality defect and expression is as in wild-type.
TS21: right ventricle cardiac muscle Present Regionally restricted 3N This mutant lacks a laterality defect and expression is as in wild-type.
Specimen 3O: embryonic day 13.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS21: heart Absent 3O This mutant has a right isomeric phenotype and expression is absent in this mutant.
Specimen 3P: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: right ventricle cardiac muscle Present Regionally restricted 3P Expression is in the ventral myocardium.
TS21: left atrium Present 3P
TS21: heart Present Regionally restricted 3P Expression is in ventral veins.
Specimen 3Q: embryonic day 13.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS21: heart Present Regionally restricted 3Q This mutant lacks a laterality defect and expression is as in wild-type.
TS21: left atrium Present Regionally restricted 3Q This mutant lacks a laterality defect and expression is as in wild-type.
TS21: right ventricle cardiac muscle Present Regionally restricted 3Q This mutant lacks a laterality defect and expression is as in wild-type.
TS21: heart ventricle Present Regionally restricted 3Q Expression is in dorsal ventricular cells.
Specimen 3R: embryonic day 13.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS21: heart Absent 3R This mutant has a right isomeric phenotype and expression is absent in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/22/2024
MGI 6.24 		The Jackson Laboratory