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Gene Expression Data
Assay Details
Assay
Reference: J:124179 Del Monte G, et al., Monitoring Notch1 activity in development: Evidence for a feedback regulatory loop. Dev Dyn. 2007 Sep;236(9):2594-614
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5789949
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-cleaved Notch1 (Val1744) antibody (anti-NICD) (#2421)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Assay notes: Antibody detects cytosolic domain of Notch1 only when cleaved between Gly1743 and Val1744.
Results
Specimen 4S: embryonic day 13.5 (more )
Note: Double labeled: green - Notch1; red - Acta2 (assay MGI:5789950).
Structure Level Pattern Image Note
TS21: dorsal aorta Present Regionally restricted 4S Nuclear expression in smooth muscle cells.
Specimen S9G/H/I: embryonic day 13.5 (more )
Note: Double labeled: green - Notch1; red - pan-cytokeratin.
Structure Level Pattern Image Note
TS21: thymus primordium Present Regionally restricted S9H/I , S9G Expressed in developing thymocytes and stromal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory